ASSOCIATION BETWEEN HASHIMOTO'S THYROIDITIS AND PAPILLARY THYROID CANCER: A SINGLE CENTER EXPERIENCE

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dc.authoridDanis, Nilay/0000-0002-3939-3089
dc.contributor.authorDanis, N.
dc.contributor.authorComlekci, A.
dc.contributor.authorYener, S.
dc.contributor.authorDurak, M.
dc.contributor.authorCalan, M.
dc.contributor.authorSolmaz, D.
dc.contributor.authorYalcin, M. M.
dc.date.accessioned2024-09-29T16:08:30Z
dc.date.available2024-09-29T16:08:30Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractPurpose. To investigate the association between papillary thyroid cancer (PTC) and Hashimoto's thyroiditis (HT). Design. This study is a retrospective study that conducted during 7 consecutive years with a median 119.5 months follow-up. Subjects and Method. Patients who underwent thyroidectomy in Dokuz Eylul University Hospital during 7 consecutive years were included. Patients' demographics, biochemical, radiological, and pathological results were retrospectively assessed. Results. Four hundred sixty nine patients were evaluated. Among 469 patients who underwent thyroidectomy, 132 (28.1%) were malignant, while 182 patients were diagnosed with HT (38.8%). PTC was ranked first at 92.4% (n: 122). The prevalence of HT was 54.9% in patients with PTC and 33.1% in patients without PTC diagnosis (p<0.001). Younger age and the presence of HT were independently associated with PTC. The presence of HT was associated with increased risk of development of PTC (OR: 2.2, %95 CI: 1.4-3.5, p<0.001) but not with TNM stage or recurrence. Lymph node metastasis at presentation was the strongest predictor of recurrence (OR: 13.9, CI: 3.5-54.6, p<0.001) Conclusions. HT was an independent risk factor for development of PTC. According to our findings, HT patients (particularly with nodular HT) should be observed carefully and thyroid fine needle aspiration biopsy (TFNAB) should be encouraged if necessary.en_US
dc.identifier.doi10.4183/aeb.2022.74
dc.identifier.endpage78en_US
dc.identifier.issn1841-0987
dc.identifier.issn1843-066X
dc.identifier.issue1en_US
dc.identifier.pmid35975248en_US
dc.identifier.scopus2-s2.0-85135586799en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage74en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2022.74
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7588
dc.identifier.volume18en_US
dc.identifier.wosWOS:000850761500011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHashimoto thyroiditisen_US
dc.subjectpapillary thyroid canceren_US
dc.subjectthyroid fine needle aspiration biopsyen_US
dc.subjectthyroid noduleen_US
dc.titleASSOCIATION BETWEEN HASHIMOTO'S THYROIDITIS AND PAPILLARY THYROID CANCER: A SINGLE CENTER EXPERIENCEen_US
dc.typeArticleen_US

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