CAN PLACENTAL HISTOPATHOLOGICAL LESIONS BE A GUIDE TO MATERNAL AND NEONATAL OUTCOMES IN PATIENTS WITH PREECLAMPSIA?

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dc.contributor.authorAtigan, A.
dc.contributor.authorKiliç, D.
dc.contributor.authorGüler, T.
dc.contributor.authorKarakaya, Y.A.
dc.date.accessioned2024-09-29T16:16:21Z
dc.date.available2024-09-29T16:16:21Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to investigate the predictive role of massive perivillous fibrinoid deposition (MPFD), syncytial knots, and accompanying histopathological features of placentas of preeclampsia (PE) on maternal and neonatal outcomes. Matherials and Methods: A retrospective clinicopathological study was conducted in a tertiary unit. In the study, 51 pregnant women admitted with PE and 55 normotensive healthy pregnant women matched for age and gestational age were compared. Information regarding clinical characteristics, neonatal findings, and placental properties such as syncytial knots, vascular structure density, placental area, volume, and weight) was retrieved. Results: Massive perivillous fibrinoid deposition, syncytial knots and decreased vessels in terminal villi were significantly frequent in the PE group compared to the controls. However, these histopathological findings were not associated with clinical and neonatal outcomes. Conclusions: Syncytial knot and perivillous fibrin deposition are significant microscopic findings of preeclampsia. However, the presence and amount of fibrin deposition were not correlated with perinatal outcome. © 2022 Istanbul Tip Fakultesi Dergisi.All rights reserved.en_US
dc.identifier.doi10.26650/IUITFD.1040208
dc.identifier.endpage432en_US
dc.identifier.issn1305-6433
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85140781948en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage425en_US
dc.identifier.urihttps://doi.org/10.26650/IUITFD.1040208
dc.identifier.urihttps://hdl.handle.net/20.500.14619/9040
dc.identifier.volume85en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIstanbul University Pressen_US
dc.relation.ispartofIstanbul Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmassive perivillous fibrinoid depositionen_US
dc.subjectneonatal outcomesen_US
dc.subjectobstetric complicationsen_US
dc.subjectPreeclampsiaen_US
dc.subjectsyncytial knotsen_US
dc.titleCAN PLACENTAL HISTOPATHOLOGICAL LESIONS BE A GUIDE TO MATERNAL AND NEONATAL OUTCOMES IN PATIENTS WITH PREECLAMPSIA?en_US
dc.title.alternativePREEKLAMPSİLİ HASTALARDA PLASENTAL HİSTOPATOLOJİK LEZYONLAR MATERNAL VE NEONATAL SONUÇLAR İÇİN BİR REHBER OLABİLİR Mİ?en_US
dc.typeArticleen_US

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