Characterization and in vitro bioactivity analysis of apatite growth on modified calcium borate silicate ceramic

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dc.authoridsaud AL-HUMAIRI, Ameer N./0000-0001-6049-387X
dc.authoridOzdemir, Olcay/0000-0001-8867-1551
dc.contributor.authorSaud, A. Najah
dc.contributor.authorKoc, Erkan
dc.contributor.authorOzdemir, Olcay
dc.date.accessioned2024-09-29T15:55:07Z
dc.date.available2024-09-29T15:55:07Z
dc.date.issued2023
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBioactive glasses are considered biocompatible materials that form a hydroxyapatite-like layer on the surface that allows strong adhesion to soft and hard tissues. This study aims to develop a method to fabricate a borate silicate ceramic biomaterial with a chemical composition of Ca11Si4B2O22 using sodium metaborate (NaBO2) as a flux. X-ray diffraction (XRD), scanning electron microscopy energy distribution spectrometer (SEM-EDS), and Fourier transform infrared spectrometer (FTIR) were used to analyze the structure, surface composition and chemical bonding of the bioactive borate silicate. In addition, the pH measurements and biodegradability behavior of the fabricated glass structures were investigated after immersion in simulated body fluid for 2, 7, 14, and 21 days, respectively. The results showed that the glass-ceramic structure, which was transferred from the crystalline phase Ca11Si4B2O22 to a hydroxyapatite phase after incubation, started on the second day. In addition, the formed hydroxyapatite crystals developed due to the prolonged immersion time, reflecting biodegradable behavior. The antimicrobial activity of the prepared ceramic showed high inhibitory activity against Enterococcus faecalis and Streptococcus mutans.en_US
dc.identifier.doi10.1016/j.ceramint.2023.06.002
dc.identifier.endpage27381en_US
dc.identifier.issn0272-8842
dc.identifier.issn1873-3956
dc.identifier.issue16en_US
dc.identifier.scopus2-s2.0-85161039514en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage27373en_US
dc.identifier.urihttps://doi.org/10.1016/j.ceramint.2023.06.002
dc.identifier.urihttps://hdl.handle.net/20.500.14619/4480
dc.identifier.volume49en_US
dc.identifier.wosWOS:001027782800001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofCeramics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBorate silicateen_US
dc.subjectSodium metaborateen_US
dc.subjectMelt-deriveden_US
dc.subjectCarbonate apatiteen_US
dc.subjectAntimicrobial activityen_US
dc.titleCharacterization and in vitro bioactivity analysis of apatite growth on modified calcium borate silicate ceramicen_US
dc.typeArticleen_US

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