Vestibular evoked myogenic potential responses in obstructive sleep apnea syndrome

Basit Öğe Kaydı
dc.authoridBayir, Omer/0000-0001-9445-6129
dc.authoridFIRAT, Hikmet/0000-0003-2594-4887
dc.contributor.authorMutlu, Murad
dc.contributor.authorBayir, Omer
dc.contributor.authorYuceege, Melike B.
dc.contributor.authorKaragoz, Tugba
dc.contributor.authorFirat, Hikmet
dc.contributor.authorOzdek, Ali
dc.contributor.authorAkin, Istemihan
dc.date.accessioned2024-09-29T15:51:04Z
dc.date.available2024-09-29T15:51:04Z
dc.date.issued2015
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObstructive sleep apnea syndrome (OSAS) provokes oxidative stress and ischemia, which affects the central nervous system. The degeneration of neurons in the brainstem due to periodic hypoxia can be evaluated by vestibular and audiologic tests. The objective of this study is to determine brainstem damage in severe OSAS patients with the help of vestibular evoked myogenic potential (VEMP) responses. Prospective, randomize, double-blind. Research-training hospital. We compared cervical vestibular evoked myogenic potential (cVEMP) responses between severe OSAS patients and a control group. 54 patients were included and divided into the OSAS group, with severe OSAS (apnea-hypopnea index, AHI > 70), and a control group with snoring without OSAS (AHI < 5). Both groups underwent cVEMP. Bilateral recordings with simultaneous binaural logon stimulations were used during VEMP recordings. The existing p1n1 and n2p2 responses, p1, n1, n2, and p2 latencies and amplitudes, and p1n1 and n2p2 intervals were measured. Statistically significant differences were revealed between patients and controls for the response rate of the p1n1, n2p2 and p1n1, n2p2 amplitudes. There were no significant differences between the two groups with respect to the latencies of p1, n1, n2 and p2, or the p1n1 and n2p2 intervals. The VEMP response rate was lower in severe OSAS patients, and all amplitudes were shorter than in healthy subjects. VEMP recordings in severe OSAS subjects demonstrates abnormalities in brainstem pathways. It appears that brainstem damage in severe OSAS can be detected by cVEMP recordings.en_US
dc.identifier.doi10.1007/s00405-014-3294-x
dc.identifier.endpage3141en_US
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue11en_US
dc.identifier.pmid25288372en_US
dc.identifier.scopus2-s2.0-84942192003en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3137en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-014-3294-x
dc.identifier.urihttps://hdl.handle.net/20.500.14619/3871
dc.identifier.volume272en_US
dc.identifier.wosWOS:000361540600007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObstructive sleep apneaen_US
dc.subjectVestibular evoked myogenic potentialsen_US
dc.subjectBrainstemen_US
dc.subjectIschemiaen_US
dc.titleVestibular evoked myogenic potential responses in obstructive sleep apnea syndromeen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu