False-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignancies

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dc.contributor.authorYasar, Z.
dc.contributor.authorAcat, M.
dc.contributor.authorOnaran, H.
dc.contributor.authorOzgül, A.
dc.contributor.authorDincer, E.H.
dc.contributor.authorCetinkaya, E.
dc.contributor.authorKorkmaz, N.A.
dc.date.accessioned2024-09-29T16:22:04Z
dc.date.available2024-09-29T16:22:04Z
dc.date.issued2015
dc.departmentKarabük Üniversitesien_US
dc.description.abstractAim 18-Fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET/CT) is an imaging modality that is often used to help differentiate benign from malignant pulmonary lesions and it has been shown to be more efficacious than conventional chest computed tomography (CT). However, some benign lesions may also show increased metabolic activity which can lead to false-positive PET findings. We aim to illustrate false positive findings of PET scan that simulate lung cancer in a variety of diseases. Methods Patients referred to Yedikule Chest Diseases and Surgery Teaching and Research Hospital with increased FDG uptake for which histological results were available over a 2-year period (2013-2014) were reviewed. Seven patients with false-positive PET/CT findings were reported in this study. Results The majority of lesions showing increased metabolic activity were due to malignant diseases. However, increased 18 F-FDG uptake was also seen in benign lesions such as active pulmonary inflammation or infection, granulomatous processes and fibrotic lesions. Conclusion The integration of clinical history, morphologic findings of lesions on the CT component, and metabolic activities of PET/CT scan can help reduce false interpretations. Interventional procedures may be needed for tissue confirmation for differential diagnosis. © 2015 Medical Association of Zenica-Doboj Canton. All rights reserved.en_US
dc.identifier.endpage46en_US
dc.identifier.issn1840-0132
dc.identifier.issue1en_US
dc.identifier.pmid25669335en_US
dc.identifier.scopus2-s2.0-84957864348en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage40en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14619/9778
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMedical Association of Zenica-Doboj Cantonen_US
dc.relation.ispartofMedicinski Glasniken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFalse–positiveen_US
dc.subjectFDGen_US
dc.subjectMimicking malignanciesen_US
dc.subjectPET scanen_US
dc.titleFalse-positive 18-fluorodeoxyglucose positron emission tomography–computed tomography (FDG PET/CT) scans mimicking malignanciesen_US
dc.typeArticleen_US

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