Intake of dietary advanced glycation end products may be associated with depression and sleep quality in young adults

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dc.authoridDemirer, Busra/0000-0003-1945-0485
dc.contributor.authorDemirer, Busra
dc.contributor.authorSamur, Gulhan
dc.date.accessioned2024-09-29T15:57:23Z
dc.date.available2024-09-29T15:57:23Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackground: This study examined the relationship between dietary intake of advanced glycation end products (dAGEs) and depression and sleep quality in young adults. Methods: This study, which included 420 university students (F = 80.2 %; M = 19.8 %), is observational and cross-sectional. Dietary AGEs intakes of individuals were taken with a 24-h food consumption record system. Measuring the depression status of the participants was evaluated with the Beck Depression Inventory (BDI), and the assessment of their sleep quality was evaluated with the Pittsburg Sleep Quality Index (PSQI). Individuals' dAGEs intakes were divided into three equal groups (low, medium, and high). The energy was adjusted in all analyzes of dAGEs intake. Study data were analyzed with the SPSS (27.0 version) and GraphPad program (8.0 version). Results: The BDI and PSQI total score averages of individuals in the high dAGEs intake group were higher than the other groups, and this difference was statistically significant (p < 0.001). There is no significant difference between individuals' dAGEs intakes and energy and macronutrient intakes. Students' dAGEs intake was affected by BDI (beta = 0.722, 95 % Cl = 0.639;0.811) and PSQI (beta = 0.286, 95 % Cl = 0.179;0.431) scores (p < 0.001). This effect persisted even when various confounding factors were included (age, gender, smoking, body mass index, chronic disease) (p < 0.001). Limitations: These data are cross-sectional, which limits the generalizability of results and establishing causeeffect relationships. Conclusion: There may be an association between dAGEs intake and the development of depression and sleep quality in young adults. Clinical intervention studies using objective measurement methods should be conducted on this issue in the future.en_US
dc.identifier.doi10.1016/j.jad.2024.02.040
dc.identifier.endpage31en_US
dc.identifier.issn0165-0327
dc.identifier.issn1573-2517
dc.identifier.pmid38360358en_US
dc.identifier.scopus2-s2.0-85185835102en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage26en_US
dc.identifier.urihttps://doi.org/10.1016/j.jad.2024.02.040
dc.identifier.urihttps://hdl.handle.net/20.500.14619/4790
dc.identifier.volume352en_US
dc.identifier.wosWOS:001188917100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Affective Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlycationen_US
dc.subjectDepressionen_US
dc.subjectSleep qualityen_US
dc.subjectEnergyen_US
dc.titleIntake of dietary advanced glycation end products may be associated with depression and sleep quality in young adultsen_US
dc.typeArticleen_US

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