Detection of breath acetone by semiconductor metal oxide nanostructures-based gas sensors: A review

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dc.authoridAhmad, Zuraini/0009-0008-3363-7127
dc.authoridPang, Ai Ling/0000-0002-4138-8537
dc.authoridChahrour, Khaled M. N./0000-0002-8799-3468
dc.authoridAhmadipour, Mohsen/0000-0002-8740-5953
dc.contributor.authorAhmadipour, Mohsen
dc.contributor.authorPang, Ai Ling
dc.contributor.authorArdani, Mohammad Rezaei
dc.contributor.authorPung, Swee-Yong
dc.contributor.authorOoi, Poh Choon
dc.contributor.authorHamzah, Azrul Azlan
dc.contributor.authorWee, M. F. Mohd Razip
dc.date.accessioned2024-09-29T16:00:27Z
dc.date.available2024-09-29T16:00:27Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractDiabetes mellitus (DM), an ailment caused by unregulated blood sugar levels, can lead to the failure of more than one organ in patients. Currently, blood tests are being conducted in scientific trials to analyse and track blood sugar and ketone levels. In this method, a drop of blood from a pricked finger is placed on a sensitive strip area, which is then pre-inserted into an electronic device to be analysed. However, this method is painful, invasive, and costly, which can be unsafe if not handled properly. Human breath analysis is a rapid and non-invasive approach for detecting different volatile organic compounds (VOCs), which could be indicators of various illnesses. In patients with DM, the body produces excessive amounts of ketones together with acetoacetate, beta-hydroxybutyrate (BOHB), and acetone. Acetone is exhaled in the breath. It is produced when the body metabolizes fat, instead of glucose, for energy. Conventional exhalation analysis techniques are based entirely on spectrometric strategies; however, they are becoming increasingly appealing from a clinical point of view with the advancement of gas sensors. This study describes modern-day improvements to semiconductor metal oxide (SMO) gas sensors for the detection of exhaled acetone. Since 2011, all the sensor materials have been used to detect low concentrations of acetone gas (0.1 ppm-20 ppm). Several parameters that affect the performance of the sensor device are mentioned in detail, including the composite materials, morphology, doping, temperature, humidity, acetone concentration, and stability of the sensor. Finally, the applicability of the sensor is discussed.en_US
dc.description.sponsorshipMinistry of Higher Education (MOHE) Malaysia [AKU-254]en_US
dc.description.sponsorshipThis work was supported by AKU-254: HICoE (Fasa II) MEMS for Biomedical Devices (artificial kindney) from Ministry of Higher Education (MOHE) Malaysia.en_US
dc.identifier.doi10.1016/j.mssp.2022.106897
dc.identifier.issn1369-8001
dc.identifier.issn1873-4081
dc.identifier.scopus2-s2.0-85133246315en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.mssp.2022.106897
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5160
dc.identifier.volume149en_US
dc.identifier.wosWOS:000821788500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofMaterials Science in Semiconductor Processingen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiabetes mellitusen_US
dc.subjectBreath acetone sensoren_US
dc.subjectFactors affectingen_US
dc.subjectApplicabilityen_US
dc.titleDetection of breath acetone by semiconductor metal oxide nanostructures-based gas sensors: A reviewen_US
dc.typeReviewen_US

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