Investigation of hearing and outer hair cell function of the cochlea in patients with vitiligo

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dc.authoridSOYLEMEZ, EMRE/0000-0002-7554-3048
dc.authoridERTUGRUL, SUHA/0000-0001-9743-6924
dc.contributor.authorErtugrul, Goksen
dc.contributor.authorErtugrul, Suha
dc.contributor.authorSoylemez, Emre
dc.date.accessioned2024-09-29T16:04:39Z
dc.date.available2024-09-29T16:04:39Z
dc.date.issued2020
dc.departmentKarabük Üniversitesien_US
dc.description.abstractVitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to determine which disease-related parameters trigger damage to cochlear melanocytes in vitiligo patients and the effect of vitiligo on the outer hair cells and hearing. Thirty-one vitiligo patients and 40 sex- and age-matched healthy volunteers were evaluated. The conventional pure tone audiometry (C-PTA) test and the distortion product otoacoustic emission (DPOAE) test were performed. There was no significant difference between vitiligo patients and controls in C-PTA test results, but the DPOAE test results were abnormal in vitiligo patients. The duration of the disease was significantly related to hypoacusis. As the duration of the disease increases, cochlear dysfunction may increase. Especially in patients with longer disease duration, otoacoustic emission tests should be performed in addition to conventional audiometry tests for early detection of damage to the outer hair cells.en_US
dc.identifier.doi10.1111/dth.13724
dc.identifier.issn1396-0296
dc.identifier.issn1529-8019
dc.identifier.issue4en_US
dc.identifier.pmid32475000en_US
dc.identifier.scopus2-s2.0-85087306684en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/dth.13724
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6231
dc.identifier.volume33en_US
dc.identifier.wosWOS:000543349100001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofDermatologic Therapyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectaudiometryen_US
dc.subjecthearing lossen_US
dc.subjectmelanocyteen_US
dc.subjectotoacoustic emissionen_US
dc.subjectvitiligoen_US
dc.titleInvestigation of hearing and outer hair cell function of the cochlea in patients with vitiligoen_US
dc.typeArticleen_US

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