Clinical characteristics of atrial fibrillation in nonagenarian population and relationship with mortality

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dc.contributor.authorCakan, Fahri
dc.contributor.authorOnalan, Orhan
dc.contributor.authorAdar, Adem
dc.contributor.authorAkbay, Ertan
dc.contributor.authorColluoglu, Inci T.
dc.contributor.authorKokturk, Ugur
dc.contributor.authorAkin, Yesim
dc.date.accessioned2024-09-29T16:06:53Z
dc.date.available2024-09-29T16:06:53Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBACKGROUND: There is a considerable amount of literature available on well-known risk factors for atrial fibrillation (AF); however, available data specifically focused on the ninth decade are scarce. The main objective of this study was to assess the demographic and clinical characteristics of AF and sinus rhythm in a nonagenarian population. METHODS: All individuals aged >90 years who were admitted to the Cardiology outpatient clinic between April 2018 and January 2019 were enrolled in the study. The demographic and clinical characteristics of all patients were recorded. All deaths that occurred during the two-year follow-up period were recorded. RESULTS: In total, 112 nonagenarian individuals were included in the study. Of these patients, 50 (44.6%) had AF. The groups showed similarities in demographic and clinical characteristics. During a mean follow-up period of 596 +/- 44 days, 39 patients (78%) in the AF group and 35 patients (56.5%) in the sinus group died. Patients with AF showed a lower overall survival distribution than those with sinus rhythm (P=0.005, log-rank test chi 2=7.734). 2 =7.734). AF was associated with an increased risk of mortality (P=0.002, hazard ratio [HR] =2.104, 95% confidence interval [CI] = 1.326-3.339) in multivariate Cox regression analysis, while waist circumference and total cholesterol (P=0.003, HR=0.969, 95% CI=0.949-0.989 and P=0.046, HR=0.993, 95% CI=0.986-1.000, respectively) showed a decreased risk of mortality. CONCLUSIONS: Atrial fibrillation is very common in individuals over the age of 90 years (44.6%). Well-known risk factors do not appear to be effective in this age group, and AF is associated with a 2.1-fold increase in the risk of mortality.en_US
dc.description.sponsorshipThe authors acknowledge Dr. Ekrem Karakaya (deceased) for his precious contribution to the study.en_US
dc.identifier.doi10.23736/S2724-5683.24.06464-0
dc.identifier.endpage384en_US
dc.identifier.issn2724-5683
dc.identifier.issn2724-5772
dc.identifier.issue4en_US
dc.identifier.pmid38934266en_US
dc.identifier.scopus2-s2.0-85197119509en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage372en_US
dc.identifier.urihttps://doi.org/10.23736/S2724-5683.24.06464-0
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7115
dc.identifier.volume72en_US
dc.identifier.wosWOS:001267821100009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofMinerva Cardiology and Angiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNonagenariansen_US
dc.subjectPrevalenceen_US
dc.subjectMortalityen_US
dc.subjectAtrial fibrillationen_US
dc.titleClinical characteristics of atrial fibrillation in nonagenarian population and relationship with mortalityen_US
dc.typeArticleen_US

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