Evaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applications

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dc.authoridAlshemary, Ammar Z/0000-0001-5367-1869
dc.authoridmuhammed, yasser/0000-0002-3118-7264
dc.contributor.authorAlshemary, Ammar Z.
dc.contributor.authorSarsik, Betul
dc.contributor.authorSalman, Nader A.
dc.contributor.authorSahin, Sitem Merve
dc.contributor.authorSahin, Mehmet Murat
dc.contributor.authorMuhammed, Yasser
dc.date.accessioned2024-09-29T16:06:41Z
dc.date.available2024-09-29T16:06:41Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIn orthopedics and traumatology surgeries, the repair of bone deformities is a concern. Pure and Cobalt (Co) doped Calcium phosphate (CaP) cements were successfully prepared in this study. The particles that had been manufactured were characterized. Three different methods were used to study the structure of the materials: X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and Scanning electron microscope (SEM). The lattice characteristics, degree of crystallinity, and particle size of pure CaP bone cement were reduced dramatically with the incorporation of Co2+ ions. The functional groups of CaP bone cements were detected via the FTIR technique. Antibacterial properties of pure and Co doped CaP bone cement were evaluated qualitatively against Escherichia coli (E. Coli, gram -), Methicillin-sensitive Staphylococcus aureus (MSSA, gram +). Methicillin-resistant Staphylococcus aureus (MRSA, gram +), Methicillin-resistant coagulase-negative staphylococci (MR-CoNS, gram +), and Pseudomonas aeruginosa (P. aeruginosa, gram -) bacteria for 24 h at 37 degrees C. After analyzing the data, it was found that the inclusion of Co2+ ions inhibited the growth of E. coli and MSSA bacteria. Antibacterial bone cements are potential material for preventing infection-related bone healing failures.en_US
dc.description.sponsorshipKarabuk University [KBUBAP FYL-2020-2031]en_US
dc.description.sponsorshipDr. Ammar Z. Alshemary appreciates KBUBAP FYL-2020-2031 funding assistance from Karabuk University. The authors would like to thank Assoc. Prof. Dr. Elcin KAL CAKMAKLIOGULLARI for her help during this work.en_US
dc.identifier.doi10.21608/ejchem.2021.110005.5013
dc.identifier.endpage336en_US
dc.identifier.issn0449-2285
dc.identifier.issn2357-0245
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85130627845en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage331en_US
dc.identifier.urihttps://doi.org/10.21608/ejchem.2021.110005.5013
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6988
dc.identifier.volume65en_US
dc.identifier.wosWOS:000804436400027en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNatl Inform & Document Centreen_US
dc.relation.ispartofEgyptian Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone cementsen_US
dc.subjectBone Cementsen_US
dc.subjectCalcium Phosphateen_US
dc.subjectCobalten_US
dc.subjectAntibacterial propertiesen_US
dc.titleEvaluation of Antibacterial Activity of Calcium Phosphates Based Bone Cements for Biomedical Applicationsen_US
dc.typeArticleen_US

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