Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study

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dc.authoridengin, velittin selcuk/0000-0002-6338-4748
dc.authoridErsoy, Suleyman/0000-0003-0001-9329
dc.contributor.authorErsoy, Suleyman
dc.contributor.authorEngin, Velittin Selcuk
dc.date.accessioned2024-09-29T16:06:40Z
dc.date.available2024-09-29T16:06:40Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractPurpose: Polypharmacy (PP) is a clinical challenge in older adults. Therefore, assessment of daily drug consumption (DDC) and its relationships is important. First-line health services have a crucial role in monitoring and prevenfmg PP. In this study, we aimed to assess DDC and investigate the risk factors for higher DDC among older adults in a pi-Unary care setting. Patients and methods: A total of 1,000 patients aged 65 years who visited Melek Ilatun Family Practice Center between December I, 2014, and August 1, 2017, were enrolled in the study. All patients were seen either at the center or in their homes, and informed consent was obtained. Comprehensive geriatric assessment was performed for each subject. Data were analyzed using SPSS software (version 17). The daily number of medicines that each patient used (DDC) regardless of whether they were prescribed was the dependent variable. Relationships between DDC and other continuous variables were examined using Pearson's correlation. For between-group comparisons of DDC, Student's i-tests were performed. Results: Univariate tests showed relationships between DDC and various demographic and clinical parameters. The variables that remained significant at the last step of a stepwise linear regression analysis were metabolic syndrome, chronic NM, incontinence, increased serum creatinine level, increased Geriatric Depression Scale scores, reported gastric disturbances, and neutrophil lymphocyte ratio. Conclusion: Along With certain chronic conditions, depressive symptoms and an inflammatory marker (neutrophillymphocyte ratio) significantly and independently related to higher DDC. Longitudinal and larger studies are ceded to further explore the multifaceted relationships of PP.en_US
dc.identifier.doi10.2147/CIA.S176329
dc.identifier.endpage2011en_US
dc.identifier.issn1178-1998
dc.identifier.pmid30410317en_US
dc.identifier.scopus2-s2.0-85056257094en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2003en_US
dc.identifier.urihttps://doi.org/10.2147/CIA.S176329
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6983
dc.identifier.volume13en_US
dc.identifier.wosWOS:000447526900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDove Medical Press Ltden_US
dc.relation.ispartofClinical Interventions in Agingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpolypharmacyen_US
dc.subjectolder adulten_US
dc.subjectprimary careen_US
dc.subjectGeriatric Depression Scaleen_US
dc.subjectmetabolic syndromeen_US
dc.subjectneutrophililymphocyte ratioen_US
dc.titleRisk factors for polypharmacy in older adults in a primary care setting: a cross-sectional studyen_US
dc.typeArticleen_US

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