Synthesis, Molecular Structure, Biological Activity, and Sensor Properties of (E)-2-[(3,5-Bis(trifluoromethyl)phenylimino)methy1]-4,6-dichlorophenol
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Maik Nauka/Interperiodica/Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In the present study, a Schiff base (E)-24(3,5-bis(trifluoromethyl)phenylimino)methyl]-4,6-dichlorophenol has been synthesized. Its spectroscopic and X-ray single -crystal data have been compared with the results of theoretical calculations based on the DFT method, as well as molecular electrostatic potential (MEP), HOMO and LUMO, and nonlinear optical (NLO) effects Antimicrobial activity of the compound has been tested against some bacteria and fungi. According to UV-Vis and agarose gel electrophoresis methods, the compound interacts with DNA electrostatically and breaks it oxidatively. Antioxidant activity of the compound measured by the DPPH method, is lower than that of BHT.
Açıklama
Anahtar Kelimeler
single crystal, DFT, DNA interactions, antioxidant, sensor applications
Kaynak
Russian Journal of General Chemistry
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
91
Sayı
2