Platelet/lymphocyte ratio is an independent predictor for osteoporosis

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dc.contributor.authorEroglu, Semra
dc.contributor.authorKaratas, Gulsah
dc.date.accessioned2024-09-29T16:06:19Z
dc.date.available2024-09-29T16:06:19Z
dc.date.issued2019
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjectives: To investigate the intercourse between the platelet/lymphocyte (P/L) and neutrophil/lymphocyte ratio (N/L), and vitamin D (Vit-D) levels in low bone mineral density (BMD) of women. Methods: Two hundred fifty-two postmenopausal female outpatients who were admitted to the obstetrics and gynecology and physical therapy clinics between July 2016 and December 2017 were retrospectively analyzed. The patients were grouped in relation to their T-score (normal [n=92], osteopenia [n=112], and PMO [n=48]). The serum levels of P/L, N/L, Vit-D, BMD and complete blood count of the patients were retrospectively examined. Results: The median P/L was significantly higher and Vit-D levels were significantly lower in the PMO group (130.75 [52.89-385] versus 123.05 [54-232.5], p=0.02 and 15.4 [4-34] versus 20.1 [4-47], p=0.003). While BMD and P/L were negatively correlated, a positive correlation between BMD and Vit-D was found. Vitamin D levels were negatively correlated with P/L (p<0.001) and N/L (p=0.04). Older age (>= 65 years), Vit-D deficiency and P/L values >125.06 were found as independent prognostic factors for PMO in regression analysis. Conclusion: Higher P/L seems to be a quite simple marker to help predict postmenopausal PMO. As seen in our study, having low levels of Vit-D is crucial for PMO.en_US
dc.identifier.doi10.15537/smj.2019.4.24009
dc.identifier.endpage366en_US
dc.identifier.issn0379-5284
dc.identifier.issue4en_US
dc.identifier.pmid30957129en_US
dc.identifier.scopus2-s2.0-85064517095en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage360en_US
dc.identifier.urihttps://doi.org/10.15537/smj.2019.4.24009
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6771
dc.identifier.volume40en_US
dc.identifier.wosWOS:000482650400006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSaudi Med Jen_US
dc.relation.ispartofSaudi Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.subjectBone-Mineral Densityen_US
dc.subjectVitamin-Den_US
dc.subjectInflammatory Biomarkersen_US
dc.subjectPostmenopausal Womenen_US
dc.subjectFractureen_US
dc.subjectRisken_US
dc.subjectSupplementationen_US
dc.subjectAssociationen_US
dc.titlePlatelet/lymphocyte ratio is an independent predictor for osteoporosisen_US
dc.typeArticleen_US

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