Aortic arch calcification: a novel parameter for prediction of masked hypertension

dc.authoridAkbay, Ertan/0000-0002-9146-0621
dc.authoridCakan, Fahri/0000-0002-5427-3480
dc.authoridAKINCI, SINAN/0000-0001-5250-5404
dc.authoridMUDERRISOGLU, IBRAHIM HALDUN/0000-0002-9635-6313
dc.contributor.authorAkbay, Ertan
dc.contributor.authorConer, Ali
dc.contributor.authorAkinci, Sinan
dc.contributor.authorAdar, Adem
dc.contributor.authorCakan, Fahri
dc.contributor.authorMuderrisoglu, Haldun
dc.date.accessioned2024-09-29T16:03:11Z
dc.date.available2024-09-29T16:03:11Z
dc.date.issued2021
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackground Masked hypertension is directly related to increased cardiovascular morbidity and mortality but remains underdiagnosed in clinical practice. The aim of the study was to search the role of aortic arch calcification (AAC) in the diagnosis of masked hypertension. Methods and results Among the patients who underwent ambulatory blood pressure monitoring (ABPM) in our clinic, those with office blood pressure (OBP) <140/90 mmHg were included in the study population. According to OBP, they were divided into two groups as normal (<130/85 mmHg) and high normal (130-139/85-89 mmHg) OBP groups. Subjects were also investigated for the presence of masked hypertension with ABPM and searched in masked hypertension and control groups. Masked hypertension was defined as in the latest 2017 ACC/AHA Hypertension guideline and was diagnosed as the daytime BP >= 135/85 mmHg and nighttime BP >= 120/70 mmHg. AAC was evaluated on direct X-ray telecardiography. Diagnosis of masked hypertension was searched depending on the presence of AAC and OBP measurements as well. A total of 216 volunteers were involved in the study [mean age 45.2 +/- 12.2 years; female gender 120 (55.5%)]. One hundred ten volunteers (50.9%) had masked hypertension according to the ABPM. AAC was significantly more common in the masked hypertension group (44.5% vs. 26.4%) (P = 0.005). AAC had a positive predictive value of 79% in those with high normal OBP in the diagnosis of masked hypertension, and also AAC had a negative predictive value of 74% in those with normal OBP. Conclusion AAC can be used as a reliable diagnostic tool to exclude and predict masked hypertension during office examination.en_US
dc.description.sponsorshipBaskent University Research Funden_US
dc.description.sponsorshipThis study was supported by the Baskent University Research Fund.en_US
dc.identifier.doi10.1097/MBP.0000000000000529
dc.identifier.endpage262en_US
dc.identifier.issn1359-5237
dc.identifier.issn1473-5725
dc.identifier.issue4en_US
dc.identifier.pmid33734125en_US
dc.identifier.scopus2-s2.0-85109537163en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage257en_US
dc.identifier.urihttps://doi.org/10.1097/MBP.0000000000000529
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5936
dc.identifier.volume26en_US
dc.identifier.wosWOS:000670036100003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofBlood Pressure Monitoringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectambulatory blood pressure monitoringen_US
dc.subjectaortic arch calcificationen_US
dc.subjectmasked hypertensionen_US
dc.titleAortic arch calcification: a novel parameter for prediction of masked hypertensionen_US
dc.typeArticleen_US

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