The Cytotoxic and Genotoxic Assays of Mg-Ag Alloy Doped with Zn, Ca, and Nd Elements

Basit Öğe Kaydı
dc.contributor.authorElen, Levent
dc.contributor.authorTuren, Yunus
dc.contributor.authorCicek, Bunyamin
dc.contributor.authorBozer, Busra Moren
dc.contributor.authorSaud, A. Najah
dc.contributor.authorKoc, Erkan
dc.date.accessioned2024-09-29T15:54:32Z
dc.date.available2024-09-29T15:54:32Z
dc.date.issued2023
dc.departmentKarabük Üniversitesien_US
dc.description.abstractMagnesium alloys are being studied for their potential as biodegradable metals, and there is a growing need for multipurpose materials, such as those with more than one use. Binary Mg-Ag alloys were developed as implant materials, combining the beneficial qualities of magnesium with silver's well-known compatibility feature. The result shows that as the amount of the added Ag in the cast alloys increased, the secondary phases (Mg4Ag and Mg54Ag17) that appeared in the structure became more pronounced, and the grains became finer. The best percentage of Ag was found to be 3%, so Ca, Zn and Nd were added, and a study of the biocompatible Mg-3Ag alloy's cytotoxicity and genotoxicity showed that the alloy is safe for cells. In conclusion, 1/1 (total material concentration) cell viability for QE-30, QZ-30, QX-30, and QZEX3000 was 79.39 +/- 1.85, 106.46 +/- 1.99, 93.55 +/- 2.4, and 141.76 +/- 2.71%, respectively. Reducing material concentration by 50% (application at 1/2 concentration) raised viability to 96.83 +/- 1.35, 108.40 +/- 1.92, 124.71 +/- 2.76, and 129.05 +/- 3.5%, indicating the as-cast Mg + 3%Ag + 0.5% Nd-Ca-Zn alloy was extremely biocompatible.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK); 1002-Short Term R&D Founding Program [119M645]en_US
dc.description.sponsorshipThis research was supported by The Scientific and Technological Research Council of Turkey (TUBITAK) with the 1002-Short Term R&D Founding Program (Project No. 119M645).en_US
dc.identifier.doi10.1007/s11665-022-07627-1
dc.identifier.endpage7347en_US
dc.identifier.issn1059-9495
dc.identifier.issn1544-1024
dc.identifier.issue16en_US
dc.identifier.scopus2-s2.0-85141601381en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage7337en_US
dc.identifier.urihttps://doi.org/10.1007/s11665-022-07627-1
dc.identifier.urihttps://hdl.handle.net/20.500.14619/4120
dc.identifier.volume32en_US
dc.identifier.wosWOS:000880533300008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Materials Engineering and Performanceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbiodegradableen_US
dc.subjectcytotoxicityen_US
dc.subjectgenotoxicityen_US
dc.subjectMg-Ag alloysen_US
dc.subjectmicrostructureen_US
dc.titleThe Cytotoxic and Genotoxic Assays of Mg-Ag Alloy Doped with Zn, Ca, and Nd Elementsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu