Social Relationships Moderate Genetic Influences on Heavy Drinking in Young Adulthood

Basit Öğe Kaydı
dc.authoridSalvatore, Jessica/0000-0001-5504-5087
dc.authoridKaprio, Jaakko/0000-0002-3716-2455
dc.authoridKorhonen, Tellervo/0000-0003-2838-3085
dc.authoridLatvala, Antti/0000-0001-5695-117X
dc.contributor.authorBarr, Peter B.
dc.contributor.authorSalvatore, Jessica E.
dc.contributor.authorMaes, Hermine H.
dc.contributor.authorKorhonen, Tellervo
dc.contributor.authorLatvala, Antti
dc.contributor.authorAliev, Fazil
dc.contributor.authorViken, Richard
dc.date.accessioned2024-09-29T16:06:18Z
dc.date.available2024-09-29T16:06:18Z
dc.date.issued2017
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: Social relationships, such as committed partnerships, limit risky behaviors like heavy drinking, in part, because of increased social control. The current analyses examine whether involvement in committed relationships or social support extend beyond a main effect to limit genetic liability in heavy drinking (gene-environment interaction) during young adulthood. Method: Using data from the young adult wave of the Finnish Twin Study, FinnTwin 12 (n = 3,269), we tested whether involvement in romantic partnerships or social support moderated genetic influences on heavy drinking using biometric twin modeling for gene-environment interaction. Results: Involvement in a romantic partnership was associated with a decline in genetic variance in both males and females, although the overall magnitude of genetic influence was greater in males. Sex differences emerged for social support: increased social support was associated with increased genetic influence for females and reduced genetic influence for males. Conclusions: These findings demonstrate that social relationships are important moderators of genetic influences on young adult alcohol use. Mechanisms of social control that are important in limiting genetic liability during adolescence extend into young adulthood. In addition, although some relationships limit genetic liability equally, others, such as extensive social networks, may operate differently across sex.en_US
dc.description.sponsorshipNational Institute on Alcohol Abuse and Alcoholism [R01AA015416, K02AA018755, K01AA024152, F32AA022269]; Academy of Finland [100499, 205585, 118555, 141054, 265240, 263278, 264146]; Scientific and Technological Research Council of Turkey [114C117]en_US
dc.description.sponsorshipThis study was supported by National Institute on Alcohol Abuse and Alcoholism Grants R01AA015416, K02AA018755, K01AA024152, and F32AA022269; Academy of Finland Grants 100499, 205585, 118555, 141054, 265240, 263278, and 264146; and Scientific and Technological Research Council of Turkey Grant 114C117. The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health, the Academy of Finland, or the Scientific and Technological Research Council of Turkey.en_US
dc.identifier.doi10.15288/jsad.2017.78.817
dc.identifier.endpage826en_US
dc.identifier.issn1937-1888
dc.identifier.issn1938-4114
dc.identifier.issue6en_US
dc.identifier.pmid29087815en_US
dc.identifier.scopus2-s2.0-85032986013en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage817en_US
dc.identifier.urihttps://doi.org/10.15288/jsad.2017.78.817
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6738
dc.identifier.volume78en_US
dc.identifier.wosWOS:000414665200003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAlcohol Res Documentation Inc Cent Alcohol Stud Rutgers Univen_US
dc.relation.ispartofJournal of Studies On Alcohol and Drugsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlcohol-Useen_US
dc.subjectEnvironment Interactionen_US
dc.subjectRomantic Relationshipsen_US
dc.subjectAdolescent Drinkingen_US
dc.subjectTurning-Pointsen_US
dc.subjectMarital-Statusen_US
dc.subjectMental-Healthen_US
dc.subjectSubstance Useen_US
dc.subjectBehavioren_US
dc.subjectSupporten_US
dc.titleSocial Relationships Moderate Genetic Influences on Heavy Drinking in Young Adulthooden_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu