Utility of non-invasive synchronized intermittent mandatory ventilation in acute cardiogenic pulmonary edema

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dc.authoridCekmen, Bora/0000-0003-3348-8375
dc.authoridBildik, Busra/0000-0002-1546-4612
dc.contributor.authorCekmen, Bora
dc.contributor.authorBildik, Busra
dc.contributor.authorBozan, Oner
dc.contributor.authorAtis, Seref Emre
dc.contributor.authorDogan, Serkan
dc.contributor.authorKocak, Abdullah Osman
dc.date.accessioned2024-09-29T15:54:55Z
dc.date.available2024-09-29T15:54:55Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackgrounds: Acute cardiogenic pulmonary edema (ACPE), one of the outcomes of acute heart failure (AHF), is a common reason in a critical condition with respiratory distress. Non-invasive synchronized intermittent manda-tory ventilation(nSIMV) mode, which includes inspiratory pressure in addition to positive end expiratory pres-sure with/without pressure support provided in the non-invasive continuous positive airway pressure plus/ pressure support(nCPAP/PS) mode can be effective in hypercarbia and the associated changes in consciousness. This study aimed to demonstrate the efficacy of nSIMV in ACPE. Methods: Patients who presented with clinical acute respiratory failure and were admitted to the critical care unit of the emergency department with the diagnosis of ACPE were included. Patients were placed on non-invasive mechanical ventilators with an oronasal mask under the nCPAP/PS and nSIMV modes. Pulse and respiratory rate, systolic and diastolic blood pressure and Glasgow Coma Scores(GCS), HACOR(heart rate, acidosis, con-sciousness, oxygenation and respiratory rate) scores, pH, PaCO2, PaO2/FiO2 and lactate at the time of admission and at 30 and 60 min were evaluated. Results: Twenty-two patients were recruited, nCPAP/PS mode was 10 and nSIMV mode was 12. Although there was no statistically significant difference between the two groups in terms of the change in the relevant param-eters from admission to 60 min, the decreases in PaCO2 and lactate levels (31.4% vs. 21.2%, p = 0.383; 68.8% vs. 47.1%, p = 0.224; respectively) and the increase in PaO2 and PaO2/FiO2 values (34% vs. 14.2%, p = 0.710 and 132.1% vs. 52.7%, p = 0.073; respectively) were higher in the nSIMV group. Conclusion: The nSIMV mode is as effective as the nCPAP/PS mode in the treatment of patients with ACPE. We be-lieve that the nSIMV mode can be preferable, particularly in patients with hypercarbia who have relatively lower GCS and oxygenation.(c) 2022 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2022.03.044
dc.identifier.endpage76en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.pmid35367682en_US
dc.identifier.scopus2-s2.0-85127334370en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage71en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2022.03.044
dc.identifier.urihttps://hdl.handle.net/20.500.14619/4357
dc.identifier.volume56en_US
dc.identifier.wosWOS:000799775900013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary edemaen_US
dc.subjectRespiratory failureen_US
dc.subjectContinuous positive airway pressureen_US
dc.subjectNoninvasive ventilationen_US
dc.titleUtility of non-invasive synchronized intermittent mandatory ventilation in acute cardiogenic pulmonary edemaen_US
dc.typeArticleen_US

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