Is the presence of Demodex folliculorum increased with impaired glucose regulation in polycystic ovary syndrome?

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dc.authorideroglu, semra/0000-0002-9959-9433
dc.contributor.authorEroglu, Semra
dc.contributor.authorCakmakliogullari, Murat
dc.contributor.authorCakmakliogullari, Elcin Kal
dc.date.accessioned2024-09-29T16:01:15Z
dc.date.available2024-09-29T16:01:15Z
dc.date.issued2020
dc.departmentKarabük Üniversitesien_US
dc.description.abstractDemodex parasites may cause skin and eyelash lesions by settling on the pilosebaceous unit. This parasite plays a role in the pathophysiology of acne in polycystic ovarian syndrome (PCOS). We aimed to examine the relationship between Demodex folliculorum and blood glucose control in patients with PCOS with skin and eyelash lesions. Forty-four patients with PCOS with skin lesions were enrolled in the study. At least two specimens were taken from the skin lesions using the standard method and at least six epilated eyelashes were taken from both eyes under a biomicroscope and evaluated using a light microscope. The demographic characteristics, body mass index (BMI) and clinical parameters of the patients were recorded. Demodex folliculorum was present at a rate of 59.1% in the skin lesions of the patients with PCOS, 40.9% in eyelash samples and 43.18% in both skin and lashes. Homeostasis model assessment of insulin resistance (HOMA-IR), glycosylated haemoglobin (HB A1c) concentrations, and BMIs were significantly higher in the patients who had D. folliculorum in skin samples than in those without (p = .010, p = .007 and p = .02). Impaired glucose regulation may explain the pathophysiology of the increased D. folliculorum presence in the skin lesions of patients with PCOS.Impact statement What is already known on this subject? Although several studies on Demodex folliculorum and PCOS have been conducted, we have not yet found a study that examines D. folliculorum parasites in the eyelashes and skin correlating with glucose regulation in PCOS. This study presents new information about the relationship between the presence of D. folliculorum and impaired glucose regulation in women with PCOS. What do the results of this study add? D. folliculorum is seen more commonly in skin lesions in patients with PCOS with impaired blood glucose regulation.en_US
dc.identifier.doi10.1080/01443615.2019.1634026
dc.identifier.endpage550en_US
dc.identifier.issn0144-3615
dc.identifier.issn1364-6893
dc.identifier.issue4en_US
dc.identifier.pmid31500491en_US
dc.identifier.scopus2-s2.0-85073792414en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage546en_US
dc.identifier.urihttps://doi.org/10.1080/01443615.2019.1634026
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5616
dc.identifier.volume40en_US
dc.identifier.wosWOS:000485559900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal of Obstetrics and Gynaecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolycystic ovary syndromeen_US
dc.subjectDemodex mitesen_US
dc.subjectskinen_US
dc.subjecteyesen_US
dc.subjectimpaired glucose regulationen_US
dc.titleIs the presence of Demodex folliculorum increased with impaired glucose regulation in polycystic ovary syndrome?en_US
dc.typeArticleen_US

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