Effect of crocin on oxidative stress in recovery from single bout of swimming exercise in rats

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dc.authoridGozukara Bag, Harika Gozde/0000-0003-1208-4072
dc.authoridAltinoz, Eyup/0000-0002-3991-9773
dc.contributor.authorAltinoz, Eyup
dc.contributor.authorOzmen, Tarik
dc.contributor.authorOner, Zulal
dc.contributor.authorElbe, Hulya
dc.contributor.authorErdemli, Mehmet E.
dc.contributor.authorBag, Harika G.
dc.date.accessioned2024-09-29T16:08:29Z
dc.date.available2024-09-29T16:08:29Z
dc.date.issued2016
dc.departmentKarabük Üniversitesien_US
dc.description.abstractPhysical exercise could cause muscle and tissue damage due to increase in the formation of free oxygen radicals during exercise. The aim of the present study was to investigate the effect of crocin on parameters associated with oxidative stress in recovery from acute swimming exercise in rats. Rats were divided into eight groups; Normal Control (NC, untreated and did not swim), Crocin Control (CC, received crocin and did not swim), Exe-1, Exe-24, Exe-48 (untreated and swam) and and Exe-Cro-1, Exe-Cro-24, Exe-Cro-48 (received crocin and swam). AST, ALP, LDH, CK, XO enzymes levels increased after swimming in untreated and crocin-treated groups, but there was a less increase in crocin-treated groups. The highest MDA levels in serum were determined in Exe-1 compared with all other groups. There was significant difference between control and exercise groups in MDA level (p = 0.033). In contrast, there was significant difference between control and exercise groups in GSH level (p < 0.001). In addition, crocin given to swimming rats significantly increased GSH levels (p < 0.05) and decreased MDA levels when compared with untreated exercise groups. In conclusion, crocin is able to protect liver and skeletal muscle tissue against exercise-induced oxidative damage by preventing reactive oxygen species (ROS) production.en_US
dc.identifier.doi10.4149/gpb_2015018
dc.identifier.endpage94en_US
dc.identifier.issn0231-5882
dc.identifier.issn1338-4325
dc.identifier.issue1en_US
dc.identifier.pmid26001290en_US
dc.identifier.scopus2-s2.0-84983455833en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage87en_US
dc.identifier.urihttps://doi.org/10.4149/gpb_2015018
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7577
dc.identifier.volume35en_US
dc.identifier.wosWOS:000368869700010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGeneral Physiol And Biophysicsen_US
dc.relation.ispartofGeneral Physiology and Biophysicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSwimming exerciseen_US
dc.subjectOxidative stressen_US
dc.subjectCrocinen_US
dc.subjectMDAen_US
dc.subjectGSHen_US
dc.titleEffect of crocin on oxidative stress in recovery from single bout of swimming exercise in ratsen_US
dc.typeArticleen_US

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