A new method that facilitates the diagnosis of endometrial cancer: the ratio of endometrial thickness to the full thickness of the uterine wall and subcutaneous adipose tissue measurements

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dc.contributor.authorGok, Soner
dc.contributor.authorAtigan, Ayhan
dc.contributor.authorGok, Berfin Can
dc.date.accessioned2024-09-29T16:09:38Z
dc.date.available2024-09-29T16:09:38Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIntroduction: The aim of the present study was to investigate the association between some risk factors and endometrial pathologies determined by transvaginal sonography (TVS), as well as the diagnostic predictive values of serum oestradiol (E2) levels, subcutaneous adipose tissue (SAT) thickness, endometrium thickness (ET), and the ratio of ET to uterine wall full thickness (UWT) in differential diagnosis of malignant, precancerous, and benign pathologies of endometrium in patients with postmenopausal bleeding (PMB) or with asymptomatic increased endometrial thickness. Material and methods: The study was conducted with 211 women who applied to the hospital with complaints of PMB or ET of 5 mm or more in their routine controls. Venous blood samples were taken for complete blood count and the measurement of E2 levels. Patients also underwent TVS; ET, UWT, and the ratio of ET to UWT were measured. Results: Menopausal age and body mass index averages were significantly higher in atypical hyperplasia and endometrial cancer (EC) groups. Endometrial thickness and endometrial thickness/uterine wall full thickness ratio measured by TVS were significantly higher in all precancerous pathologies and EC. Subcutaneous adipose tissue thickness was significantly higher in all precancerous pathologies and EC. Oestradiol levels were higher in the atypical hyperplasia and EC groups. Conclusions: Postmenopausal bleeding is a common symptom of EC, but in some cases this disease may occur asymptomatically. Measurement of the endometrium thickness, and the ratio of endometrium thickness/ uterine wall full thickness and SAT thickness by sonography has a high predictive value for this disease.en_US
dc.identifier.doi10.5114/pm.2024.136961
dc.identifier.endpage30en_US
dc.identifier.issn1643-8876
dc.identifier.issn2299-0038
dc.identifier.issue1en_US
dc.identifier.pmid38690066en_US
dc.identifier.scopus2-s2.0-85191027980en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage25en_US
dc.identifier.urihttps://doi.org/10.5114/pm.2024.136961
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7692
dc.identifier.volume23en_US
dc.identifier.wosWOS:001201841500004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofMenopause Review-Przeglad Menopauzalnyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectendometrial canceren_US
dc.subjectsonographyen_US
dc.subjectPMBen_US
dc.subjectendometrial hyperplasiaen_US
dc.subjectendometrial thicknessen_US
dc.subjectsubcu taneous adipose tissueen_US
dc.titleA new method that facilitates the diagnosis of endometrial cancer: the ratio of endometrial thickness to the full thickness of the uterine wall and subcutaneous adipose tissue measurementsen_US
dc.typeArticleen_US

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