An evaluation of thyroid autoimmunity in patients with beta thalassemia minor: A case-control study

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dc.authoridBenli, Ali Ramazan/0000-0003-0039-1497
dc.contributor.authorBenli, Ali Ramazan
dc.contributor.authorYildiz, Sati Sena
dc.contributor.authorCikrikcioglu, Mehmet Ali
dc.date.accessioned2024-09-29T16:05:12Z
dc.date.available2024-09-29T16:05:12Z
dc.date.issued2017
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective: The tendency to autoimmune diseases has been reported to be increased in beta thalassemia minor (BTM). The aim of this study was to evaluate whether thyroid autoimmunity is higher in BTM. Methods: Patients with BTM (n= 86) and a healthy control group (n= 93) were included in this cross- sectional casecontrol study. The two groups were compared in terms of anti-thyroglobulin (anti-TG) and anti-thyroid peroxidase (anti-TPO) and thyroid hormones. Results: In the BTM group, thyroid hormones and serum anti-TG and anti-TPO antibody levels were not statistically different from those of the control group. The BTM and control groups were similar in terms of anti-thyroid antibody (ATA) positivity prevalence. In the BTM group, anti-TG was 11.6% and anti-TPO was 14% positive, while these values were 14% and 12.9% positive, respectively in the control group (p=0.806 and p=0.989, respectively). The proportion of anti-TG and/or anti-TPO antibody positive subjects was found to be 20.9% in the BTM group, and 20.4% in the control group (p=0.919). The ratios of subjects with euthyroidism, hyperthyroidism and hypothyroidism were similar in both groups. Conclusions: As the thyroid autoimmunity prevalence in the BTM group was not increased compared to the control group, it can be considered that there is no necessity for routine ATA and thyroid hormone testing in subjects with BTM.en_US
dc.identifier.doi10.12669/pjms.335.13210
dc.identifier.endpage1111en_US
dc.identifier.issn1682-024X
dc.identifier.issue5en_US
dc.identifier.pmid29142547en_US
dc.identifier.scopus2-s2.0-85032741927en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1106en_US
dc.identifier.urihttps://doi.org/10.12669/pjms.335.13210
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6570
dc.identifier.volume33en_US
dc.identifier.wosWOS:000416095500012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherProfessional Medical Publicationsen_US
dc.relation.ispartofPakistan Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-thyroid peroxidaseen_US
dc.subjectAnti-thyroglobulinen_US
dc.subjectBeta thalassemia minoren_US
dc.subjectThyroid hormonesen_US
dc.titleAn evaluation of thyroid autoimmunity in patients with beta thalassemia minor: A case-control studyen_US
dc.typeArticleen_US

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