Studies on DNA Interaction with 2(3),9(10), 16(17), 23(24)-Tetrakis 2((4-Phenoxyphenyl) Diazeylbenzoic acid)phthalocyaninato Zinc (II) Compound

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dc.contributor.authorArslantas, Ali
dc.contributor.authorAgirtas, Mehmet Salih
dc.date.accessioned2024-09-29T15:50:50Z
dc.date.available2024-09-29T15:50:50Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIn this study, 2(3), 9(10), 16(17), 23(24)-tetrakis 2((4-phenoxyphenyl) diazeylbenzoic acid)phthalocyaninato zinc (II) compound was chosen to study DNA binding activities. The binding activities of zinc (II) phthalocyanine compound bearing 2(3),9(10), 16(17), 23(24)-tetrakis 2((4-Phenoxyphenyl) diazeylbenzoic acid) ligand with Calf Thymus (CT)-DNA was investigated using absorption titration, fluorescence spectroscopy, cyclic voltammetry and thermal melting profile in a Tris-HCl buffer system at pH7.0. In addition to these methods, gel electrophoresis and viscosity measurements were also carried out to determine DNA binding activities with compound 6 in a buffer solution. The results indicated that compound 6 interacts with CT-DNA through partial intercalation binding mode.en_US
dc.description.sponsorshipCommission of Scientific Research Projects of Karabuk Universityen_US
dc.description.sponsorshipThis work was supported by the Commission of Scientific Research Projects of Karabuk University.en_US
dc.identifier.doi10.1002/slct.201800172
dc.identifier.endpage1760en_US
dc.identifier.issn2365-6549
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85042125044en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1755en_US
dc.identifier.urihttps://doi.org/10.1002/slct.201800172
dc.identifier.urihttps://hdl.handle.net/20.500.14619/3746
dc.identifier.volume3en_US
dc.identifier.wosWOS:000425012500022en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofChemistryselecten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAbsorption spectroscopyen_US
dc.subjectCyclic voltammetryen_US
dc.subjectDNA bindingen_US
dc.subjectMetallo phthalocyaninesen_US
dc.titleStudies on DNA Interaction with 2(3),9(10), 16(17), 23(24)-Tetrakis 2((4-Phenoxyphenyl) Diazeylbenzoic acid)phthalocyaninato Zinc (II) Compounden_US
dc.typeArticleen_US

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