Simulation of creep in non-homogenous samples of human cortical bone

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dc.authoridCotton, John/0000-0003-4029-2565
dc.authoridWinwood, Keith/0000-0002-8696-9976
dc.authoridZIOUPOS, PETER/0000-0002-0123-2706
dc.contributor.authorErtas, Ahmet H.
dc.contributor.authorWinwood, Keith
dc.contributor.authorZioupos, Peter
dc.contributor.authorCotton, John R.
dc.date.accessioned2024-09-29T16:02:47Z
dc.date.available2024-09-29T16:02:47Z
dc.date.issued2012
dc.departmentKarabük Üniversitesien_US
dc.description.abstractCharacterising the mechanisms causing viscoelastic mechanical properties of human cortical bone, as well as understanding sources of variation, is important in predicting response of the bone to creep and fatigue loads. Any better understanding, when incorporated into simulations including finite element analysis, would assist bioengineers, clinicians and biomedical scientists. In this study, we used an empirically verified model of creep strain accumulation, in a simulation of 10 non-homogeneous samples, which were created from micro-CT scans of human cortical bone of the femur midshaft obtained from a 74-year-old female cadaver. These non-homogeneous samples incorporate the presence of Haversian canals and resorption cavities. The influence of inhomogeneity on the response and variation in the samples in both creep and stress relaxation tests are examined. The relationship between steady-state creep rate, applied loads (stress relaxation and creep tests) and microstructure, that is bone apparent porosity, is obtained. These relations may provide insight into damage accumulation of whole human bones and be relevant to studies on osteoporosis.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey, TUBITAKen_US
dc.description.sponsorshipWe would like to acknowledge the support by The Scientific and Technological Research Council of Turkey, TUBITAK.en_US
dc.identifier.doi10.1080/10255842.2011.575069
dc.identifier.endpage1128en_US
dc.identifier.issn1025-5842
dc.identifier.issue10en_US
dc.identifier.pmid21574078en_US
dc.identifier.scopus2-s2.0-84866316386en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1121en_US
dc.identifier.urihttps://doi.org/10.1080/10255842.2011.575069
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5715
dc.identifier.volume15en_US
dc.identifier.wosWOS:000308724600010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofComputer Methods in Biomechanics and Biomedical Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthuman cortical boneen_US
dc.subjectcreepen_US
dc.subjectstress relaxationen_US
dc.subjectcreep testen_US
dc.subjectfinite element analysisen_US
dc.titleSimulation of creep in non-homogenous samples of human cortical boneen_US
dc.typeArticleen_US

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