Quantitative Evaluation of Normal Aqueductal Cerebrospinal Fluid Flow Using Phase-Contrast Cine MRI According to Age and Sex

dc.authoridKahraman, Aysegul Sagir/0000-0002-2147-1181
dc.authoridOner, Serkan/0000-0002-7802-880X
dc.authoridCay, Mahmut/0000-0002-7757-055X
dc.contributor.authorOner, Zulal
dc.contributor.authorKahraman, Aysegul Sagir
dc.contributor.authorKose, Evren
dc.contributor.authorOner, Serkan
dc.contributor.authorKavakli, Ahmet
dc.contributor.authorCay, Mahmut
dc.contributor.authorOzbag, Davut
dc.date.accessioned2024-09-29T15:50:38Z
dc.date.available2024-09-29T15:50:38Z
dc.date.issued2017
dc.departmentKarabük Üniversitesien_US
dc.description.abstractThe aim of this study was cerebrospinal fluid (CSF) flow quantification in the cerebral aqueduct using phase-contrast cine magnetic resonance imaging (PCC-MRI) according to both sexes and three different age groups to obtain normative data. Seventy two volunteers with no cerebral pathology were included in this study. Subjects were divided into three age groups: 20-34 years, 35-49 years, and 50-65 years including equal gender groups. CSF flow's quantitatively evaluation was performed with images that were obtained by 1.5 T Magnetic Resonance (MR) unit from cerebral aqueduct level on the semi-axial plan. Between groups, peak velocity (cm sec21), average velocity (cm/s), forward volume (mL), reverse volume (mL), net forward volume (mL), and average flow over range (ml/ min)values of current flowing through aqueduct and average aqueductal areas were compared. There were no statistically significant differences in CSF flow parameters among different age groups and between sexes (P> 0.05). There was a statistically significant difference in average cerebral aqueduct area between the age group of 50-65 years and the other age groups (P50.002). The average aqueductal area was higher in the age group of 50-65 years. Normal aqueductal CSF flow parameters evaluated with PCC-MRI don't show a significant difference by age and sex. We have achieved the lower and upper values of these parameters would be useful in future clinical studies. The size of aqueductal area may also be explained by atrophy-dependent ventricular system dilatation in the elderly. (C) 2016 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/ar.23514
dc.identifier.endpage555en_US
dc.identifier.issn1932-8486
dc.identifier.issn1932-8494
dc.identifier.issue3en_US
dc.identifier.pmid27863121en_US
dc.identifier.scopus2-s2.0-85012872078en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage549en_US
dc.identifier.urihttps://doi.org/10.1002/ar.23514
dc.identifier.urihttps://hdl.handle.net/20.500.14619/3642
dc.identifier.volume300en_US
dc.identifier.wosWOS:000396836400009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAnatomical Record-Advances in Integrative Anatomy and Evolutionary Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPCC-MRIen_US
dc.subjectageen_US
dc.subjectaqueductus cerebrien_US
dc.subjectCSFen_US
dc.subjectsexen_US
dc.titleQuantitative Evaluation of Normal Aqueductal Cerebrospinal Fluid Flow Using Phase-Contrast Cine MRI According to Age and Sexen_US
dc.typeArticleen_US

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