The Evaluation of Ophthalmic Findings in Women Patients With Iron and Vitamin B12 Deficiency Anemia

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dc.authoridcoskun, mehmet/0000-0001-7315-2994
dc.contributor.authorCoskun, Mehmet
dc.contributor.authorSevencan, Nurhayat O.
dc.date.accessioned2024-09-29T16:04:54Z
dc.date.available2024-09-29T16:04:54Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractPurpose: To determine whether there are differences in the central corneal thickness (CCT), retinal nerve fiber layer (RNFL), and ganglion cell-inner plexiform layer (GC-IPL) in women with iron deficiency anemia (IDA) and vitamin B12 deficiency anemia (B12DA). Methods: The patients were divided and evaluated in three groups as IDA (group 1), combined IDA-B12DA (group 2), and healthy females (group 3). Each group constituted 35 subjects. co , endothelial cell density (CD), the coefficient of variation (CV), and hexagonality (HEX) values were evaluated. Superior, nasal, inferior, and temporal retinal nerve fiber analysis were done, and mean thickness of GC-IPL complex was also evaluated. Results: CCT was found to be less (thin CCT) in group 2 as compared to group 1 and group 3 (P = 0.016 and P = 0.013, respectively). While CD measurements did not vary significantly between the groups, CV value was found to be lower in the control group as compared to that in the other groups (P = 0.001 and P = 0.002, respectively). HEX and the thicknesses of all RNFL and GC-IPL were lower in both the anemic groups as compared to the control group (P = 0.012 and P = 0.013, respectively); however, no significant difference was determined between the anemia groups. Conclusions: It should be noted that anemia is a common clinical picture particularly seen in women, and there may be a tendency toward corneal and retinal disorders in these patients. The present study found that presence in the patients with IDA and with combined IDA-B12DA may have influenced endothelial functions; also the patients with anemia had significantly thinner CCT than healthy controls. Translational Relevance: Optical coherence tomography and specular microscopy measurements may provide important data for early diagnosis and treatment of both corneal and retinal diseases according to the type of anemia in anemic women.en_US
dc.identifier.doi10.1167/tvst.7.4.16
dc.identifier.issn2164-2591
dc.identifier.issue4en_US
dc.identifier.pmid30159209en_US
dc.identifier.scopus2-s2.0-85052370025en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1167/tvst.7.4.16
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6401
dc.identifier.volume7en_US
dc.identifier.wosWOS:000443671400006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Research Vision Ophthalmology Incen_US
dc.relation.ispartofTranslational Vision Science & Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectiron deficiency anemiaen_US
dc.subjectvitamin B12 deficiency anemiaen_US
dc.subjectcentral corneal thicknessen_US
dc.subjectretinal nerve fiber layeren_US
dc.subjectganglion cell-inner plexiform layeren_US
dc.titleThe Evaluation of Ophthalmic Findings in Women Patients With Iron and Vitamin B12 Deficiency Anemiaen_US
dc.typeArticleen_US

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