Accuracy of the methods used to estimate glomerular filtration rate compared to 24-hour urinary creatinine clearance in patients with chronic spinal cord injury

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dc.authoridHazer, Burcu/0000-0002-3170-345X
dc.authoridAKYUZ, MUFIT/0000-0001-5590-5075
dc.authoridOnder, Fatih Oguz/0000-0003-2845-201X
dc.authoridBaran, Sirin/0000-0003-0153-973X
dc.contributor.authorHazer, Burcu
dc.contributor.authorOnder, Fatih Oguz
dc.contributor.authorMetli, Neslihan Bilge
dc.contributor.authorAslan, Sirin Baran
dc.contributor.authorYalcin, Elif
dc.contributor.authorAkyuz, Mufit
dc.date.accessioned2024-09-29T16:02:51Z
dc.date.available2024-09-29T16:02:51Z
dc.date.issued2023
dc.departmentKarabük Üniversitesien_US
dc.description.abstractObjective To compare the accuracy of glomerular filtration rate (GFR) estimation by 24-hour urinary creatinine clearance with GFR estimation by the Modification of Diet in Renal Disease (MDRD) equation, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, the Mayo Clinic Quadratic equation (MCQE), and the modified Cockcroft-Gault formula in patients with spinal cord injury (SCI). Design Cross-sectional study. Participants Fifty-nine consecutive subjects, who were admitted to our hospital SCI rehabilitation and no additional acute medical disorders, were enrolled in this study. A 24-hour urine sample was collected for the determination of 24-hour urinary creatinine clearance, which was assumed as the standard technique for estimation of the GFR. The accuracy of several estimation formulas includes the 4-variable MDRD equation, the 6-variable MDRD equation, the Cockcroft and Gault equation, the CKD-EPI equation, and the MCQE. Results GFRs calculated by the Cockcroft-Gault equation and 4-variable MDRD were significantly different from the 24-hour urinary creatinine clearance, whereas there were no significant differences in GFRs calculated by CKD-EPI (P = 1.000), Mayo Clinic Quadratic formula (P = 0.794), and 6-variable MDRD equations (P = 0.435) and 24-hour urinary creatinine clearance. Both the 6-variable MDRD equation and CKD-EPI were accurate within +/- 20 of the reference methods in 52.54% of the subjects. Conclusions Among the methods used for estimation of the GFR including the 4- and 6-variable MDRD, the CKD-EPI, the modified Cockcroft-Gault equation, and the MCQE, the 6-variable MDRD equation and the CKD-EPI demonstrated best performance to estimate the GFR. However, none of the formulas were sufficient to estimate the GFR in SCI patients accurately.en_US
dc.identifier.doi10.1080/10790268.2021.1975084
dc.identifier.endpage236en_US
dc.identifier.issn1079-0268
dc.identifier.issn2045-7723
dc.identifier.issue2en_US
dc.identifier.pmid34698612en_US
dc.identifier.scopus2-s2.0-85118235970en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage231en_US
dc.identifier.urihttps://doi.org/10.1080/10790268.2021.1975084
dc.identifier.urihttps://hdl.handle.net/20.500.14619/5740
dc.identifier.volume46en_US
dc.identifier.wosWOS:000711256600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Spinal Cord Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCockcroft-Gault creatinine clearanceen_US
dc.subjectModification of Diet in Renal Disease equationen_US
dc.subjectChronic Kidney Disease Epidemiology Collaboration equationen_US
dc.subjectMayo Clinic Quadratic equationen_US
dc.subjectSpinal cord injuryen_US
dc.subjectGlomerular filtration rateen_US
dc.titleAccuracy of the methods used to estimate glomerular filtration rate compared to 24-hour urinary creatinine clearance in patients with chronic spinal cord injuryen_US
dc.typeArticleen_US

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