The role of serum vitamin D levels in vitiligo

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dc.authoridAktas, Habibullah/0000-0001-9239-1659
dc.authoridKaragun, Ebru/0000-0002-5032-7429
dc.contributor.authorKaragun, Ebru
dc.contributor.authorErgin, Can
dc.contributor.authorBaysak, Sevim
dc.contributor.authorErden, Gonul
dc.contributor.authorAktas, Habibullah
dc.contributor.authorEkiz, Ozlem
dc.date.accessioned2024-09-29T16:09:38Z
dc.date.available2024-09-29T16:09:38Z
dc.date.issued2016
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIntroduction: Vitiligo is a common acquired pigmentary skin disorder. Vitamin D is responsible for skin pigmentation, increases tyrosinase activity and melanogenesis, and exhibits immunoregulatory functions. Low levels of vitamin D are associated with many autoimmune diseases, including systemic lupus, diabetes mellitus, rheumatoid arthritis, multiple sclerosis and alopecia areata. Few reports have evaluated serum vitamin D levels in vitiligo patients, and their results are conflicting. Aim: To evaluate serum vitamin D levels of vitiligo patients and compare the results with controls. Material and methods: In total, 50 vitiligo patients and 47 controls were enrolled in the study. Vitamin D levels were measured from blood samples. Group comparisons were performed using appropriate statistical methods. Results: The patients had lower serum vitamin D levels than the controls, but this difference was not significant (p = 0.570). Conclusions: It remains unknown whether vitamin D deficiency causes vitiligo. Larger controlled studies are required to prove whether low circulating vitamin D is a causative factor in vitiligo.en_US
dc.identifier.doi10.5114/pdia.2016.59507
dc.identifier.endpage302en_US
dc.identifier.issn1642-395X
dc.identifier.issue4en_US
dc.identifier.pmid27605903en_US
dc.identifier.scopus2-s2.0-84983436727en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage300en_US
dc.identifier.urihttps://doi.org/10.5114/pdia.2016.59507
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7688
dc.identifier.volume33en_US
dc.identifier.wosWOS:000382410900011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofPostepy Dermatologii I Alergologiien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectvitiligoen_US
dc.subjectvitamin Den_US
dc.subjectautoimmune diseasesen_US
dc.subjectetiopathogenesisen_US
dc.titleThe role of serum vitamin D levels in vitiligoen_US
dc.typeArticleen_US

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