Effects of Smoking on Very-Long Term Mortality after First ST Elevation Myocardial Infarction

dc.authoridSAHIN, YUSUF BOZKURT/0000-0003-3523-8783
dc.contributor.authorKiziltunc, Emrullah
dc.contributor.authorSahin, Yusuf Bozkurt
dc.contributor.authorTopal, Salih
dc.contributor.authorDuzenli, Mehmet Akif
dc.contributor.authorKarakaya, Ekrem
dc.contributor.authorAygul, Nazif
dc.contributor.authorTopsakal, Ramazan
dc.date.accessioned2024-09-29T16:08:17Z
dc.date.available2024-09-29T16:08:17Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackground: The smoking paradox has been a matter of debate for acute myocardial infarction patients for more than two decades. Although there is huge evidence claiming that is no real paradox, publications supporting better outcomes in post-MI smokers are still being released. Objective: To explore the effect of smoking on very long-term mortality after ST Elevation myocardial infarction (STEMI). Methods: This study included STEMI patients who were diagnosed between the years of 2004-2006 at three tertiary centers. Patients were categorized according to tobacco exposure (Group 1: non-smokers; Group 2: <20 package*years users, Group 3: 20-40 package*years users, Group 4: >40 package*years users). A Cox regression model was used to estimate the relative risks for very long-term mortality. P value <0.05 was considered as statistically significant. Results: There were 313 patients (201 smokers, 112 non-smokers) who were followed-up for a median period of 174 months. Smokers were younger (54 +/- 9 vs. 62 +/- 11, p: <0.001), and the presence of cardiometabolic risk factors were more prevalent in non-smokers. A univariate analysis of the impact of the smoking habit on mortality revealed a better survival curve in Group 2 than in Group 1. However, after adjustment for confounders, it was observed that smokers had a significantly increased risk of death. The relative risk became higher with increased exposure (Group 2 vs. Group 1; HR: 1.141; 95% CI: 0.599 to 2.171, Group 3 vs Group 1; HR: 2.130; 95% CI: 1.236 to 3.670, Group 4 vs Group 1; HR: 2.602; 95% CI: 1.461 to 4.634). Conclusion: Smoking gradually increases the risk of all-cause mortality after STEMI.en_US
dc.identifier.doi10.36660/abc.20201036
dc.identifier.endpage31en_US
dc.identifier.issn0066-782X
dc.identifier.issue1en_US
dc.identifier.pmid35195205en_US
dc.identifier.scopus2-s2.0-85125155084en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage24en_US
dc.identifier.urihttps://doi.org/10.36660/abc.20201036
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7461
dc.identifier.volume118en_US
dc.identifier.wosWOS:000760363600006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherArquivos Brasileiros Cardiologiaen_US
dc.relation.ispartofArquivos Brasileiros De Cardiologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTobacco Use Disorderen_US
dc.subjectNicotine/adverse effectsen_US
dc.subjectST Elevation Myocardial Infarction/complicationsen_US
dc.subjectRisk Factorsen_US
dc.subjectMortalityen_US
dc.titleEffects of Smoking on Very-Long Term Mortality after First ST Elevation Myocardial Infarctionen_US
dc.typeArticleen_US

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