Incorporation of B and La oxides into bioactive glass: in vitro studies for bone regeneration applications

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dc.contributor.authorBadraddin, R.
dc.contributor.authorKoc, E.
dc.contributor.authorSaud, A. N.
dc.date.accessioned2024-09-29T16:06:17Z
dc.date.available2024-09-29T16:06:17Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBone tissue engineering seeks to regenerate damaged tissues using biocompatible scaffolds that mimic bone minerals. This study focuses on scaffolds based 45S5 bioactive glass (45% SiO2, 24.5% Na2O, 6% P2O5, 24.5% CaO) doped with boron and lanthanum oxides. These scaffolds, produced via conventional melting, form a hydroxyapatite layer, promoting strong bone integration. Result of DTA, XRD, FTIR, SEM, and EDS, showed doping led to crystalline phase identification, silicate network confirmation, and detection of calcium phosphorus deposits. Doping also increased pH, degradation kinetics, and antibacterial activity. These findings suggest that boron and lanthanum-doped 45S5 scaffolds have potential in bone regeneration applications.en_US
dc.description.sponsorshipScientific Research Projects Coordination Unit of Karabuk University [KBUEBAP-23-YL-122]en_US
dc.description.sponsorshipThis work was supported by the Scientific Research Projects Coordination Unit of Karabuk University. Project number: KBUEBAP-23-YL-122.en_US
dc.identifier.doi10.15251/DJNB.2024.193.1173
dc.identifier.endpage1186en_US
dc.identifier.issn1842-3582
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85202554557en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1173en_US
dc.identifier.urihttps://doi.org/10.15251/DJNB.2024.193.1173
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6736
dc.identifier.volume19en_US
dc.identifier.wosWOS:001292159100005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVirtual Co Physics Srlen_US
dc.relation.ispartofDigest Journal of Nanomaterials and Biostructuresen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBioactive glassen_US
dc.subjectDopingen_US
dc.subjectBioactivityen_US
dc.subjectHydroxyapatiteen_US
dc.subjectMechanical propertiesen_US
dc.titleIncorporation of B and La oxides into bioactive glass: in vitro studies for bone regeneration applicationsen_US
dc.typeArticleen_US

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