Assessing Safety of Pneumatic Tube System (PTS) for Patients with Very Low Hematologic Parameters

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dc.authoridERKURT, MEHMET ALI/0000-0002-3285-417X
dc.authoridBERBER, Ilhami/0000-0003-3312-8476
dc.authoridKAYIS, Seyit Ali/0000-0003-4791-8946
dc.authoridKaya, Emin/0000-0001-8605-8497
dc.contributor.authorKoroglu, Mustafa
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorKuku, Irfan
dc.contributor.authorKaya, Emin
dc.contributor.authorBerber, Ilhami
dc.contributor.authorNizam, Ilknur
dc.contributor.authorYagar, Yavuz
dc.date.accessioned2024-09-29T16:05:12Z
dc.date.available2024-09-29T16:05:12Z
dc.date.issued2016
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackground: Preventive interventions save lives during the process of chemotherapy for hematologic malignancies, when a hematology laboratory can ensure accurate results. The use of a pneumatic tube system (PTS) is associated with measurement errors and unnecessary transfusions. The aim of this study was to evaluate pre-analytical errors associated with transportation method (PTS versus hand-delivered) and to investigate whether there are unnecessary transfusion events in pancytopenia leukemia patients with very low hematological parameters. Material/Methods: A total of 140 paired blood collections were performed for hemogram and biochemistry assays. Paired EDTA and serum gel blood samples were collected from 58 cases with acute leukemia on different days. For each pair, one sample was hand-delivered by a courier (Group 1) while the other sample was transported through a PTS (Group 2). Results: The hand-delivered method showed that some platelet transfusions were unnecessary for different thrombocyte cut-off values. Calculated unnecessary platelet (PLT) transfusion ratios when using PTS (PLT <30x10(3)/mu L, 16.3%; PLT <25x10(3)/mu L, 16.4%; PLT <20x10(3)/mu L, 80.3%; PLT <15x10(3)/mu L, 48.6%; and PLT <10x10(3)/mu L, 150.0%) were found to be statistically significant (p=0.002, p=0.046, p<0.000, p=0.028, and p<0.000, respectively). In contrast, for RBC transfusion ratios, although the ratios were high in Group 2, we found no significant difference between the two groups; (HGB <8.0 g/dL, 23.3%; HGB <9.0 g/dL, 25.0%, HGB<10.0 g/dL, 19.3%) and (p=0.002, p=0.085, p<0.160, and p=0.235, respectively). Conclusions: Although our results cannot be universally applied, physicians should be careful, skeptical, and suspicious of transfusion decisions in hematology clinics and consider potential analytical and pre-analytical errors in cases of severe cytopenia when using PTS.en_US
dc.description.sponsorshipScientific Research Projects Service of Inonu Universityen_US
dc.description.sponsorshipScientific Research Projects Service of Inonu Universityen_US
dc.identifier.doi10.12659/MSM.898164
dc.identifier.endpage1333en_US
dc.identifier.issn1643-3750
dc.identifier.pmid27097101en_US
dc.identifier.scopus2-s2.0-84964310796en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1329en_US
dc.identifier.urihttps://doi.org/10.12659/MSM.898164
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6568
dc.identifier.volume22en_US
dc.identifier.wosWOS:000374474500002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Scientific Information, Incen_US
dc.relation.ispartofMedical Science Monitoren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlood Component Transfusionen_US
dc.subjectLeukemia, Myeloid, Acuteen_US
dc.subjectTransportationen_US
dc.titleAssessing Safety of Pneumatic Tube System (PTS) for Patients with Very Low Hematologic Parametersen_US
dc.typeArticleen_US

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