Investigation (In-Vitro) of Antiproliferative Properties of Pseudopediastrum boryanum (Turpin) E. Hegewald Extracts in Various Cancer Cell Lines

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dc.contributor.authorDemiriz Yucer, Tugba
dc.date.accessioned2024-09-29T16:06:34Z
dc.date.available2024-09-29T16:06:34Z
dc.date.issued2024
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIn this study, the antiproliferative effects of Pseudopediastrum boryanum isolated and cultured from Tokat Ye & scedil;il & imath;rmak River benthic habitats were investigated with in-vitro experiments. The Anticancer activity of algae extracts was tested in cancer cell lines using the BrdU cell proliferation ELISA method. Vero (African Green Monkey Kidney Tumour Cells) and HeLa (Human Uterine Carcinoma Cells) were examined in concentrations of 100, 250 and 500 mu g mL-1.-1 . As a result of antiproliferative tests, P. boryanum was found to have effective anticancer properties. P. boryanum extract concentrations of 250 and 500 mu g mL-1-1 had a significant cytotoxic effect on Vero and HeLa cell lines after 24 hours. According to the results, P. boryanum is estimated to be a good option for quantitative pharmaceutical analyses and could be evaluated in the pharmaceutical industry.en_US
dc.description.sponsorshipACKNOWLEDGMENT The author thanks Prof.Dr. Koksal Pabuccu for his help in the diagnosis of algae species.en_US
dc.identifier.doi10.18016/ksutarimdoga.vi.1420650
dc.identifier.endpage1031en_US
dc.identifier.issn2619-9149
dc.identifier.issue5en_US
dc.identifier.startpage1026en_US
dc.identifier.urihttps://doi.org/10.18016/ksutarimdoga.vi.1420650
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6914
dc.identifier.volume27en_US
dc.identifier.wosWOS:001309840400004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherKahramanmaras Sutcu Imam Univ Rektorluguen_US
dc.relation.ispartofKsu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Natureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntiproliferative effecten_US
dc.subjectBrdUen_US
dc.subjectChlorophytaen_US
dc.subjectPseudopediastrum boryanumen_US
dc.titleInvestigation (In-Vitro) of Antiproliferative Properties of Pseudopediastrum boryanum (Turpin) E. Hegewald Extracts in Various Cancer Cell Linesen_US
dc.typeArticleen_US

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