EARLY BLOOD TRANSFUSION MAY PREVENT POSTOPERATIVE COGNITIVE DYSFUNCTION AFTER HIP ARTHROPLASTY IN ELDERLY PATIENTS

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dc.contributor.authorMutlu, Tansel
dc.contributor.authorDasar, Uygar
dc.date.accessioned2024-09-29T16:07:55Z
dc.date.available2024-09-29T16:07:55Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIntroduction: The number of joint arthroplasties in the elderly continues to increase with the increase in elderly population. Postoperative cognitive dysfunction is an important complication after surgery in elderly patients. However, the exact cause of postoperative cognitive dysfunction and factors contributing to its development remain unknown. We aimed to determine whether blood loss during or after surgery and the approach for the replacement of this loss affected postoperative cognitive dysfunction frequency and duration. Materials and Method: A prospective study of elderly (>75 years) patients who underwent total/partial hip arthroplasty due to femoral neck or intertrochanteric fractures was conducted. Patients were randomised into two groups. The first group underwent transfusion when haemoglobin values reduced below 9.0 mg/dL, whereas the second group underwent earlier blood transfusion according to the volume of blood loss during and after surgery. All groups were similar in terms of factors considered to be associated with postoperative cognitive dysfunction. An experienced neurologist assessed patients' cognitive functions using the Standardized Mini-Mental Status Examination test and clinical examinations pre- and postoperatively. Results: In total, 48 patients in the first group and 13 in the second group (early intervention group) were diagnosed with postoperative cognitive dysfunction. The duration of cognitive dysfunction was significantly lower in the second group (10.8 +/- 1.2 vs. 8.9 +/- 1.5 days; p<0.001). Conclusion: Although the causal relationship between blood loss and postoperative cognitive dysfunction has not been elucidated in this study, our results demonstrate that postoperative cognitive dysfunction frequency and duration may be reduced by early replacement of blood loss in elderly patients who undergo total/partial hip arthroplasty.en_US
dc.identifier.doi10.31086/tjgeri.2018344055
dc.identifier.endpage409en_US
dc.identifier.issn1304-2947
dc.identifier.issn1307-9948
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85057259318en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage402en_US
dc.identifier.trdizinid300747en_US
dc.identifier.urihttps://doi.org/10.31086/tjgeri.2018344055
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/300747
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7236
dc.identifier.volume21en_US
dc.identifier.wosWOS:000448434300013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGunes Kitabevi Ltd Stien_US
dc.relation.ispartofTurkish Journal of Geriatrics-Turk Geriatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArthroplastyen_US
dc.subjectReplacementen_US
dc.subjectHipen_US
dc.subjectCognitive Dysfunctionen_US
dc.subjectBlood Lossen_US
dc.subjectSurgicalen_US
dc.subjectBlood Transfusionsen_US
dc.titleEARLY BLOOD TRANSFUSION MAY PREVENT POSTOPERATIVE COGNITIVE DYSFUNCTION AFTER HIP ARTHROPLASTY IN ELDERLY PATIENTSen_US
dc.typeArticleen_US

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