Impact of B2O3 and La2O3 addition on structural, mechanical and biological properties of hydroxyapatite

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dc.authoridAlshemary, Ammar Z/0000-0001-5367-1869
dc.authoridTezcaner, Aysen/0000-0003-4292-5856
dc.authoridEvis, Zafer/0000-0002-7518-8162
dc.authoridKhoshsima, Sina/0000-0001-9110-0012
dc.contributor.authorKhoshsima, Sina
dc.contributor.authorAlshemary, Ammar Z.
dc.contributor.authorTezcaner, Aysen
dc.contributor.authorSurdem, Sedat
dc.contributor.authorEvis, Zafer
dc.date.accessioned2024-09-29T16:06:44Z
dc.date.available2024-09-29T16:06:44Z
dc.date.issued2018
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIn this study, hydroxyapatite-B2O3-La2O3 composites (with <= 20 wt.% B2O3 and <= 2 wt.% La2O3) were synthesized via wet precipitation method and calcined at 1100 degrees C for 1 h. X-ray diffraction (XRD) analysis revealed the existence of the pure hydroxyapatite (HA) phase with high crystallinity. Characteristic absorption bands of HA were also observed in Fourier transform infrared spectra. Furthermore, scanning electron microscopy images demonstrated that the addition of B2O3 and La2O3 into HA enhanced the particle growth. Mechanical properties of the composites were studied by diametral tensile test and the results showed that incorporation of 10 wt.% B2O3 and 2 wt.% La2O3 led to a 39% increase in tensile strength (compared to the pure HA). In vitro cytocompatibility of HA-B2O3-La2O3 composites was investigated using Osteosarcoma Cell Lines (Saos-2). Incorporation of B2O3 and La2O3 into HA had no toxic effect towards the cells. Based on its tensile strength properties and biological response, composite of 88 wt.% HA, 10 wt.% B2O3 and 2 wt.% La2O3 was suggested as a promising composite for bone tissue engineering applications.en_US
dc.identifier.doi10.2298/PAC1802143K
dc.identifier.endpage152en_US
dc.identifier.issn1820-6131
dc.identifier.issn2406-1034
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85049869241en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://doi.org/10.2298/PAC1802143K
dc.identifier.urihttps://hdl.handle.net/20.500.14619/7019
dc.identifier.volume12en_US
dc.identifier.wosWOS:000437062200008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniv Novi Sad, Fac Technologyen_US
dc.relation.ispartofProcessing and Application of Ceramicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectbiocompositesen_US
dc.subjecthydroxyapatiteen_US
dc.subjectB2O3en_US
dc.subjectLa2O3en_US
dc.subjectmicrostructureen_US
dc.subjecttensile strengthen_US
dc.subjectSaos-2 cellsen_US
dc.titleImpact of B2O3 and La2O3 addition on structural, mechanical and biological properties of hydroxyapatiteen_US
dc.typeArticleen_US

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