A Comparative Study on DNA Binding Properties of 2,10,16,24-Tetrakis 4-(4-hydroxyphenyl)-1-phenylethyl) phenoxy)-Substituted Co(II) and Mg(II) Phthalocyanine Compounds
Küçük Resim Yok
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, DNA binding properties of 2,10,16,24-tetrakis4-(4-hydroxyphenyl)-1-phenylethyl)phenoxy)phthalocyaninato Co(II) and Mg(II) compounds were analyzed. CT-DNA was used to determine DNA binding properties of Co(II) (4) and Mg(II) (5) phthalocyanine compounds. The DNA binding properties of compounds 4 and 5 were investigated using electronic absorption titration, fluorescence spectroscopy, cyclic voltammetry, thermal denaturation study, electrophoresis and viscosity measurements in Tris-buffer (pH 7.0). The results indicated that Co(II) and Mg(II) phthalocyanine compounds have strong affinity for CT-DNA through intercalation.
Açıklama
Anahtar Kelimeler
Calf thymus DNA, Cyclic voltammetry, DNA-binding, Phthalocyanine compounds, UV/ Vis. spectroscopy
Kaynak
Chemistryselect
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
2
Sayı
27
