A Comparative Study on DNA Binding Properties of 2,10,16,24-Tetrakis 4-(4-hydroxyphenyl)-1-phenylethyl) phenoxy)-Substituted Co(II) and Mg(II) Phthalocyanine Compounds

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dc.contributor.authorArslantas, Ali
dc.contributor.authorAgirtas, Mehmet Salih
dc.date.accessioned2024-09-29T15:50:50Z
dc.date.available2024-09-29T15:50:50Z
dc.date.issued2017
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIn this study, DNA binding properties of 2,10,16,24-tetrakis4-(4-hydroxyphenyl)-1-phenylethyl)phenoxy)phthalocyaninato Co(II) and Mg(II) compounds were analyzed. CT-DNA was used to determine DNA binding properties of Co(II) (4) and Mg(II) (5) phthalocyanine compounds. The DNA binding properties of compounds 4 and 5 were investigated using electronic absorption titration, fluorescence spectroscopy, cyclic voltammetry, thermal denaturation study, electrophoresis and viscosity measurements in Tris-buffer (pH 7.0). The results indicated that Co(II) and Mg(II) phthalocyanine compounds have strong affinity for CT-DNA through intercalation.en_US
dc.description.sponsorshipCommission of Scientific Research Projects of Karabuk Universityen_US
dc.description.sponsorshipThis work was supported by the Commission of Scientific Research Projects of Karabuk University.en_US
dc.identifier.doi10.1002/slct.201701224
dc.identifier.endpage8665en_US
dc.identifier.issn2365-6549
dc.identifier.issue27en_US
dc.identifier.scopus2-s2.0-85041810872en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage8661en_US
dc.identifier.urihttps://doi.org/10.1002/slct.201701224
dc.identifier.urihttps://hdl.handle.net/20.500.14619/3743
dc.identifier.volume2en_US
dc.identifier.wosWOS:000416746900061en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofChemistryselecten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCalf thymus DNAen_US
dc.subjectCyclic voltammetryen_US
dc.subjectDNA-bindingen_US
dc.subjectPhthalocyanine compoundsen_US
dc.subjectUV/ Vis. spectroscopyen_US
dc.titleA Comparative Study on DNA Binding Properties of 2,10,16,24-Tetrakis 4-(4-hydroxyphenyl)-1-phenylethyl) phenoxy)-Substituted Co(II) and Mg(II) Phthalocyanine Compoundsen_US
dc.typeArticleen_US

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