Intergenerational Continuity in Parents' and Adolescents' Externalizing Problems: The Role of Life Events and Their Interaction With GABRA2

Küçük Resim Yok

Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Amer Psychological Assoc

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

We examine whether parental externalizing behavior has an indirect effect on adolescent externalizing behavior via elevations in life events, and whether this indirect effect is further qualified by an interaction between life events and adolescents' GABRA2 genotype (rs279871). We use data from 2 samples: the Child Development Project (CDP; n = 324) and FinnTwin12 (n = 802). In CDP, repeated measures of life events, mother-reported adolescent externalizing, and teacher-reported adolescent externalizing were used. In FinnTwin12, life events and externalizing were assessed at age 14. Parental externalizing was indexed by measures of antisocial behavior and alcohol problems or alcohol dependence symptoms in both samples. In CDP, parental externalizing was associated with more life events, and the association between life events and subsequent adolescent externalizing varied as a function of GABRA2 genotype (p <= .05). The association between life events and subsequent adolescent externalizing was stronger for adolescents with 0 copies of the G minor allele compared to those with 1 or 2 copies of the minor allele. Parallel moderation trends were observed in FinnTwin12 (p <= .11). The discussion focuses on how the strength of intergenerational pathways for externalizing psychopathology may differ as a function of adolescent-level individual differences.

Açıklama

Anahtar Kelimeler

externalizing, GABRA2, gene-environment interaction, life events, intergenerational continuity

Kaynak

Journal of Abnormal Psychology

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

124

Sayı

3

Künye