MESOPOROUS SULPHATE DOPED HYDROXYAPATITE NANOPARTICLES FOR CONTROLLED RELEASE OF PROTEINS

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dc.authoridmuhammed, yasser/0000-0002-3118-7264
dc.contributor.authorAlshemary, Ammar Z.
dc.contributor.authorMuhammed, Yasser
dc.contributor.authorSalman, Nader A.
dc.contributor.authorMotameni, Ali
dc.contributor.authorGurbuz, Riza
dc.date.accessioned2024-09-29T16:06:07Z
dc.date.available2024-09-29T16:06:07Z
dc.date.issued2022
dc.departmentKarabük Üniversitesien_US
dc.description.abstractThe purpose of this study is to synthesize and characterize the mesoporous nanostructure of Hydroxyapatite (HA), evaluate the impact of the addition of sulphate ions (SO42-) on the microstructure properties of HA, and assess the ability of the prepared materials to be used as a carrier for Bovine serum albumin (BSA) protein. This study successfully synthesized 0.07 mole of SO42-substituted HA using the reflux microwave-assisted wet precipitation method and fully characterized it using modern techniques. In particular, XRD, XPS, Raman, FESEM, and BET techniques were used to explore the micro-structure properties of materials. The results shows that the addition of SO42-ions amplified the lattice parameters and surface area of HA, and the particles shape was changed from semi-spherical to rod like shape. Adsorption and desorption of protein molecules were evaluated using BSA protein for 24 h at 37 degrees C. BSA loading capacity and release behaviours were significantly improved with the incorporation of SO42-ions. The SO4- HA materials hold a promising future for being used as a carrier for protein molecules.en_US
dc.identifier.doi10.13168/cs.2022.0040
dc.identifier.endpage452en_US
dc.identifier.issn0862-5468
dc.identifier.issn1804-5847
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85140342048en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage447en_US
dc.identifier.urihttps://doi.org/10.13168/cs.2022.0040
dc.identifier.urihttps://hdl.handle.net/20.500.14619/6633
dc.identifier.volume66en_US
dc.identifier.wosWOS:000867410800001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniv Chemistry & Technology, Pragueen_US
dc.relation.ispartofCeramics-Silikatyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHydroxyapatiteen_US
dc.subjectSulphateen_US
dc.subjectCharacterizationsen_US
dc.subjectAdsorption and desorptionen_US
dc.subjectProteinen_US
dc.titleMESOPOROUS SULPHATE DOPED HYDROXYAPATITE NANOPARTICLES FOR CONTROLLED RELEASE OF PROTEINSen_US
dc.typeArticleen_US

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