Adenovirus-36 infection and obesity: A case control study of Turkish women with polycystic ovary syndrome

Basit Öğe Kaydı
dc.authorideroglu, semra/0000-0002-9959-9433
dc.contributor.authorCakmakliogullari, Elcin Kal
dc.contributor.authorEroglu, Semra
dc.date.accessioned2024-09-29T15:55:16Z
dc.date.available2024-09-29T15:55:16Z
dc.date.issued2021
dc.departmentKarabük Üniversitesien_US
dc.description.abstractBackground and aims: Adenovirus-36 (Ad-36) seropositivity has been shown to be involved in the aetiology of obesity. The aim of this study was to examine Ad-36 positivity in obese and normal-weight patients with polycystic ovary syndrome (PCOS). Methods: There were two groups including 92 and 110 subjects. This study was a prospective casecontrol study. The enzyme-immunoassay method was used to quantitatively determine antibodies (Abs) specific to human Ad-36 in the serum samples. Age, body mass index (BMI), fasting glucose levels and insulin levels of the participants were recorded. The PCOS and control group patients were divided into two groups: the overweight group with BMI >= 25 kg/m(2) and non-obese group with BMI <25 kg/m(2). Results: Ad-36 Ab positivity in the PCOS group was found to be significantly higher than that in the control group (p < 0.001). Ad-36 Ab positivity was significantly higher in the PCOS obese group than in the control obese group (p < 0.001). Ad-36 Ab positivity and BMI >= 25 kg/m(2) were identified as independent predictors of PCOS in logistic regression analysis. Conclusion: Ad-36 Ab positivity was significantly higher in the obese/overweight PCOS patients. Obesity can be prevented in patients with PCOS by treating Ad-36. (C) 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipKarabuk University [17-KP-348]en_US
dc.description.sponsorshipThis work was supported by the Karabuk University under Grant number 17-KP-348.en_US
dc.identifier.doi10.1016/j.dsx.2021.01.019
dc.identifier.endpage418en_US
dc.identifier.issn1871-4021
dc.identifier.issn1878-0334
dc.identifier.issue1en_US
dc.identifier.pmid33581595en_US
dc.identifier.scopus2-s2.0-85100606927en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage415en_US
dc.identifier.urihttps://doi.org/10.1016/j.dsx.2021.01.019
dc.identifier.urihttps://hdl.handle.net/20.500.14619/4558
dc.identifier.volume15en_US
dc.identifier.wosWOS:000624905300075en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofDiabetes & Metabolic Syndrome-Clinical Research & Reviewsen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolycystic ovary syndromeen_US
dc.subjectObesityen_US
dc.subjectAdenovirus-36en_US
dc.subjectHomeostasis model assessment of insulin resistanceen_US
dc.titleAdenovirus-36 infection and obesity: A case control study of Turkish women with polycystic ovary syndromeen_US
dc.typeReviewen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu