Synthesis, Structural Characterization, and Biological Evaluation of Novel Substituted 1,3-Thiazole Derivatives Containing Schiff Bases
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, thiazole derivatives containing Schiff bases (7-9 a-f) were synthesized in moderate to high yields (49-94%) using the Hantzsch reaction with thiosemicarbazone derivatives (5a-c) and 2bromo- 1-phenylethanone derivatives (6a-f). The structures of synthesized compounds were elucidated by IR, H-1 NMR, C-13 NMR, elemental analyses, mass spectroscopy and X-ray diffraction analysis techniques. Moreover, the synthesized compounds were tested for their in vitro antifungal activity and most of them exhibited moderate to good activity against Fusariumoxysporumf.sp. lycopersici.
Açıklama
Anahtar Kelimeler
In-Vitro, Spectral Characterization, Antimicrobial Activity, Antifungal Activities, Thiazole Derivatives, Crystal-Structure, Complexes, Design, Antibacterial, Inhibitors
Kaynak
Journal of Heterocyclic Chemistry
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
54
Sayı
1
