Synthesis, Structural Characterization, and Biological Evaluation of Novel Substituted 1,3-Thiazole Derivatives Containing Schiff Bases

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dc.authoridTAHTACI, HAKAN/0000-0002-1557-6315
dc.authoridkarakurt, tuncay/0000-0001-6944-9883
dc.contributor.authorTahtaci, Hakan
dc.contributor.authorEr, Mustafa
dc.contributor.authorKarakurt, Tuncay
dc.contributor.authorOnaran, Abdurrahman
dc.date.accessioned2024-09-29T15:50:43Z
dc.date.available2024-09-29T15:50:43Z
dc.date.issued2017
dc.departmentKarabük Üniversitesien_US
dc.description.abstractIn this study, thiazole derivatives containing Schiff bases (7-9 a-f) were synthesized in moderate to high yields (49-94%) using the Hantzsch reaction with thiosemicarbazone derivatives (5a-c) and 2bromo- 1-phenylethanone derivatives (6a-f). The structures of synthesized compounds were elucidated by IR, H-1 NMR, C-13 NMR, elemental analyses, mass spectroscopy and X-ray diffraction analysis techniques. Moreover, the synthesized compounds were tested for their in vitro antifungal activity and most of them exhibited moderate to good activity against Fusariumoxysporumf.sp. lycopersici.en_US
dc.description.sponsorshipKarabuk University [KBU-BAP-14/1-DS-030]en_US
dc.description.sponsorshipThe financial support under the contract (KBU-BAP-14/1-DS-030) from the Karabuk University is gratefully acknowledged.en_US
dc.identifier.doi10.1002/jhet.2565
dc.identifier.endpage193en_US
dc.identifier.issn0022-152X
dc.identifier.issn1943-5193
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85010443410en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage183en_US
dc.identifier.urihttps://doi.org/10.1002/jhet.2565
dc.identifier.urihttps://hdl.handle.net/20.500.14619/3705
dc.identifier.volume54en_US
dc.identifier.wosWOS:000394058900023en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Heterocyclic Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIn-Vitroen_US
dc.subjectSpectral Characterizationen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectAntifungal Activitiesen_US
dc.subjectThiazole Derivativesen_US
dc.subjectCrystal-Structureen_US
dc.subjectComplexesen_US
dc.subjectDesignen_US
dc.subjectAntibacterialen_US
dc.subjectInhibitorsen_US
dc.titleSynthesis, Structural Characterization, and Biological Evaluation of Novel Substituted 1,3-Thiazole Derivatives Containing Schiff Basesen_US
dc.typeArticleen_US

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